Schröder Annika K, Tauchert Sascha, Ortmann Olaf, Diedrich Klaus, Weiss Jürgen M
Department of Gynaecology and Obstetrics, University of Schleswig-Holstein, Campus Luebeck, Germany.
Ann Med. 2004;36(6):426-39. doi: 10.1080/07853890410035296.
With a prevalence of 5%-10% the polycystic ovary syndrome (PCOS) is an exceptionally common disorder of premenopausal women. According to prospective studies, women with PCOS present abnormal glucose tolerance and diabetes mellitus in 31%-35% and 7.5%-10%, respectively. PCOS patients have a higher prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes and dyslipidaemia. The rate of spontaneous abortions as well as the risk to develop gestational or type 2 diabetes is increased in PCOS. Therefore, PCOS is not only a reproductive problem but a complex endocrine disease with important health implications. The role of the glucose metabolism in PCOS, the health consequences and possible interventions are reviewed in this article.
多囊卵巢综合征（PCOS）在绝经前女性中极为常见，患病率为5%-10%。根据前瞻性研究，PCOS女性出现糖耐量异常和糖尿病的比例分别为31%-35%和7.5%-10%。PCOS患者患心血管危险因素如高血压、2型糖尿病和血脂异常的几率更高。PCOS患者自然流产率以及发生妊娠期糖尿病或2型糖尿病的风险均增加。因此，PCOS不仅是一个生殖问题，还是一种具有重要健康影响的复杂内分泌疾病。本文综述了葡萄糖代谢在PCOS中的作用、健康后果及可能的干预措施。
