Otsuka Hideki, Morita Naomi, Yamashita Kyo, Nishitani Hiromu
Department of Radiology, Graduate School of Medicine, University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Ann Nucl Med. 2007 Dec;21(10):593-6. doi: 10.1007/s12149-007-0069-0. Epub 2007 Dec 25.
We report the fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT) findings of autoimmune pancreatitis (AIP) associated with idiopathic retroperitoneal fibrosis. A 69-year-old male patient was admitted to our hospital with obstructive jaundice. Six months prior to this admission, he was treated with steroid therapy for retroperitoneal fibrosis. Laboratory data showed that elevated T-bil, C-reactive protein, amylase and immunoglobulin 4, and antinuclear antibodies were positive. Clinical history, laboratory data, CT image, and magnetic resonance imaging led to a diagnosis of autoimmune pancreatitis. To investigate the inflammatory activity, FDG-PET/CT was undertaken. FDG-PET/CT demonstrated diffuse intense FDG uptake in the enlarged pancreas and diffuse mild uptake in the region of the abdominal aorta-bilateral iliac arteries. A dilated right renal pelvis and upper ureter, corresponding to hydronephrosis probably caused by retroperitoneal fibrosis, were shown. An FDG-PET/CT was useful to evaluate inflammatory activity and morphological imaging, and supported our diagnosis of AIP and retroperitoneal fibrosis.
我们报告了与特发性腹膜后纤维化相关的自身免疫性胰腺炎（AIP）的氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）/计算机断层扫描（CT）结果。一名69岁男性患者因梗阻性黄疸入院。此次入院前6个月，他因腹膜后纤维化接受了类固醇治疗。实验室数据显示总胆红素、C反应蛋白、淀粉酶和免疫球蛋白4升高，抗核抗体呈阳性。临床病史、实验室数据、CT图像和磁共振成像结果确诊为自身免疫性胰腺炎。为了研究炎症活动情况，进行了FDG-PET/CT检查。FDG-PET/CT显示肿大的胰腺有弥漫性强烈的FDG摄取，腹主动脉-双侧髂动脉区域有弥漫性轻度摄取。显示右侧肾盂和上段输尿管扩张，这可能是由腹膜后纤维化导致的肾积水。FDG-PET/CT有助于评估炎症活动和形态学成像，并支持我们对AIP和腹膜后纤维化的诊断。
