Kokles R
Arch Exp Veterinarmed. 1975;29(5):781-8.
In this first report of the isolation of reovirus from mink, isolates were obtained from 18 to 26 young mink with viral enteritis, by using cultures of cat kidney cells. The isolated also produced cytopathic changes in cell cultures of mink kidney, dog kidney, piglet kidney, calf kidney, bovine embryonic kidney and calf testis. A characteristic feature was the formation of eosinophilic inclusion bodies in the cytoplasma of culture cells. Haemagglutination tests were negative with erythrocytes from cat, rabbit, pig, horse and cattle. Attempts to infect old and young mink, kittens and ferrets with tissue culture material failed. It was not known to what extent this second infection with reovirus influenced the course of mink viral enteritis.
在关于从水貂中分离呼肠孤病毒的首篇报告中，通过使用猫肾细胞培养物，从18至26只患有病毒性肠炎的幼龄水貂中获得了病毒分离株。这些分离株在水貂肾、犬肾、仔猪肾、犊牛肾、牛胚胎肾和犊牛睾丸的细胞培养物中也产生了细胞病变效应。一个特征性表现是在培养细胞的细胞质中形成嗜酸性包涵体。用猫、兔、猪、马和牛的红细胞进行血凝试验呈阴性。用组织培养材料感染老龄和幼龄水貂、小猫和雪貂的尝试均告失败。尚不清楚呼肠孤病毒的二次感染对水貂病毒性肠炎病程的影响程度。
