Chung Hee-Young, Sung Heungsup, Lee Mi-Young, Yoon Nam Sup, Lee Seung Geun, Suh Dong-Jin, Kim Mi-Na
Department of Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Korean J Lab Med. 2007 Oct;27(5):351-4. doi: 10.3343/kjlm.2007.27.5.351.
Atopobium rimae, previously Lactobacillus rimae, is a strictly anaerobic, non-spore forming grampositive rod which was frequently isolated from odontogenic infection. We report a case of A. rimae bacteremia. A 47-yr-old man with liver cirrhosis was admitted to the hospital via emergency room due to fever and chill. His abdominal and pelvic computed tomography revealed a small abscess near the left adrenal gland. Three sets of blood cultures were taken and non-spore forming, grampositive rods were detected in all anaerobic vials. This isolate grew small nonhemolytic, gray-white translucent colonies on Brucella blood agar and was obligatory anaerobic on air-tolerance test. This organism was negative for catalase, indole, nitrate-reduction and beta-lactamase and failed to identify by Vitek ANI card (bioMerieux, France). 16S rRNA sequences of this showed 99.8% homology of the published sequence of A. rimae (GenBank accession number AF292371). Aspirates of periadrenal abscess grew Escherichia coli and Peptostreptococcus micros. He was treated with metronidazole and imipenem and follow-up cultures of blood were negative at days 4 and 10. To our knowledge, this is the first report of bacteremia of A. rimae.
齿龈阿托波菌，以前称为齿龈乳杆菌，是一种严格厌氧、无芽孢形成的革兰氏阳性杆菌，常从牙源性感染中分离出来。我们报告一例齿龈阿托波菌菌血症病例。一名47岁的肝硬化男性因发热和寒战经急诊入院。他的腹部和盆腔计算机断层扫描显示左肾上腺附近有一个小脓肿。采集了三组血培养物，在所有厌氧瓶中均检测到无芽孢形成的革兰氏阳性杆菌。该分离株在布鲁氏菌血琼脂上生长出小的非溶血性、灰白色半透明菌落，在耐氧试验中为专性厌氧菌。该菌过氧化氢酶、吲哚、硝酸盐还原和β-内酰胺酶检测均为阴性，无法通过Vitek ANI卡（法国生物梅里埃公司）鉴定。该菌的16S rRNA序列与已发表的齿龈阿托波菌序列（GenBank登录号AF292371）显示出99.8%的同源性。肾上腺周围脓肿的抽吸物培养出大肠杆菌和微小消化链球菌。他接受了甲硝唑和亚胺培南治疗，第4天和第10天的血培养复查均为阴性。据我们所知，这是首例齿龈阿托波菌菌血症报告。
