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[正常血压与高血压前期心血管危险因素的比较]

[Comparison of cardiovascular risk factors between normotension and prehypertension].

作者信息

Nah Eun Hee, Kim Hee Chul

机构信息

Korea Association of Health Promotion, Seoul, Korea.

出版信息

Korean J Lab Med. 2007 Oct;27(5):377-81. doi: 10.3343/kjlm.2007.27.5.377.

Abstract

BACKGROUND

The individuals with prehypertension are known to progress to hypertension, one of the risk factors of cardiovascular disease, more readily than the group of normal blood pressure. This study was performed to investigate the differences in the risk factors of cardiovascular disease between normotensive and prehypertensive groups, and to identify the determinants of prehypertension.

METHODS

Normotensive (N=3,732) and prehypertensive individuals (N=676) were selected from the people who underwent routine medical checkups at the Health Promotion Center (Seoul, Korea). The age, body mass index (BMI), fasting blood glucose, total cholesterol, triglyceride, LDL-cholesterol (C), HDL-C, high sensitivity C-reactive protein (hsCRP), lipoprotein(a) [Lp(a)], and the number of white blood cell were compared between the normotensive and prehypertensive groups.

RESULTS

The age, BMI, fasting blood glucose, triglyceride, and total cholesterol were higher in the males and females in the prehypertensive group than in the normotensive group. LDL-C, however, was higher and HDL-C was lower in the females in the prehypertensive group than in the normotensive group. The determinants of prehypertension were found to be age, BMI, and triglyceride.

CONCLUSIONS

There were differences in the risk factors of cardiovascular disease between the prehypertensive and normotensive groups.

摘要

背景

已知血压正常高值个体比正常血压组个体更容易进展为高血压,而高血压是心血管疾病的危险因素之一。本研究旨在调查血压正常组和血压正常高值组之间心血管疾病危险因素的差异,并确定血压正常高值的决定因素。

方法

从韩国首尔健康促进中心接受常规体检的人群中选取血压正常者(N = 3732)和血压正常高值个体(N = 676)。比较血压正常组和血压正常高值组之间的年龄、体重指数(BMI)、空腹血糖、总胆固醇、甘油三酯、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、高敏C反应蛋白(hsCRP)、脂蛋白(a) [Lp(a)]以及白细胞数量。

结果

血压正常高值组的男性和女性的年龄、BMI、空腹血糖、甘油三酯和总胆固醇均高于血压正常组。然而,血压正常高值组女性的LDL-C较高,HDL-C较低。发现血压正常高值的决定因素为年龄、BMI和甘油三酯。

结论

血压正常高值组和血压正常组之间心血管疾病危险因素存在差异。

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