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嗜铬细胞瘤:高血压与低血压交替出现的周期性发作。

Pheochromocytoma: cyclic attacks of hypertension alternating with hypotension.

作者信息

Kobal Sergio L, Paran Esther, Jamali Aamer, Mizrahi Solly, Siegel Robert J, Leor Jonathan

机构信息

Department of Surgery A, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Nat Clin Pract Cardiovasc Med. 2008 Jan;5(1):53-7. doi: 10.1038/ncpcardio1054.

DOI:10.1038/ncpcardio1054
PMID:18094673
Abstract

BACKGROUND

A 52-year-old woman was admitted to hospital with recurrent episodes of chest and abdominal pain, dyspnea, palpitations and diaphoresis. Continuous blood pressure recordings revealed rhythmic alternation between episodes of severe hypertension and episodes of hypotension. This cyclic hemodynamic crisis continued for 2 hours, with each cycle lasting around 15 min.

INVESTIGATIONS

Physical examination, electrocardiography, chest radiography, continuous intra-arterial pressure monitoring, blood and urine analysis, echocardiography, abdominal CT and 131I miodobenzylguanidine scanning.

DIAGNOSIS

Pheochromocytoma--a catecholamine secreting tumor.

MANAGEMENT

Intravenous phentolamine and fluids, oral doxazosin and surgical removal of the tumor.

摘要

背景

一名52岁女性因反复出现胸痛、腹痛、呼吸困难、心悸和多汗入院。连续血压记录显示在严重高血压发作和低血压发作之间有节律性交替。这种周期性血液动力学危机持续了2小时,每个周期持续约15分钟。

检查

体格检查、心电图、胸部X线检查、连续动脉内压力监测、血液和尿液分析、超声心动图、腹部CT和131I间碘苄胍扫描。

诊断

嗜铬细胞瘤——一种分泌儿茶酚胺的肿瘤。

治疗

静脉注射酚妥拉明和补液,口服多沙唑嗪并手术切除肿瘤。

相似文献

1
Pheochromocytoma: cyclic attacks of hypertension alternating with hypotension.嗜铬细胞瘤:高血压与低血压交替出现的周期性发作。
Nat Clin Pract Cardiovasc Med. 2008 Jan;5(1):53-7. doi: 10.1038/ncpcardio1054.
2
Histopathological analysis of spontaneous large necrosis of adrenal pheochromocytoma manifested as acute attacks of alternating hypertension and hypotension: a case report.表现为高血压与低血压交替急性发作的肾上腺嗜铬细胞瘤自发性大片坏死的组织病理学分析:一例报告
J Med Case Rep. 2016 Oct 12;10(1):279. doi: 10.1186/s13256-016-1068-3.
3
Peripartum hypertension from pheochromocytoma: a rare and challenging entity.嗜铬细胞瘤所致围产期高血压:一种罕见且具有挑战性的病症。
Am J Hypertens. 2005 Oct;18(10):1306-12. doi: 10.1016/j.amjhyper.2005.04.021.
4
Rapid cyclic fluctuations of blood pressure associated with an adrenal pheochromocytoma.与肾上腺嗜铬细胞瘤相关的血压快速周期性波动。
Hypertension. 1984 Mar-Apr;6(2 Pt 1):281-4.
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Pheochromocytoma.嗜铬细胞瘤
Nat Clin Pract Cardiovasc Med. 2008 Feb;5(2):E1. doi: 10.1038/ncpcardio1131.
6
[The nephrotic syndrome and pheochromocytoma. A report of a rare clinical case].[肾病综合征与嗜铬细胞瘤。一例罕见临床病例报告]
Clin Ter. 1994 Sep;145(9):199-203.
7
Modern management of pheochromocytoma.嗜铬细胞瘤的现代管理
Nat Clin Pract Urol. 2007 Nov;4(11):630-3. doi: 10.1038/ncpuro0962.
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Radiating abdominal pain and hypertension.放射性腹痛和高血压。
Am J Med. 2009 Dec;122(12):1103-5. doi: 10.1016/j.amjmed.2009.07.007.
9
Cardiogenic shock with basal transient left ventricular ballooning (Takotsubo-like cardiomyopathy) as first presentation of pheochromocytoma.以基底节短暂性左心室球囊样变(Takotsubo 样心肌病)为首发表现的心原性休克合并嗜铬细胞瘤。
J Cardiovasc Med (Hagerstown). 2010 Jul;11(7):507-10. doi: 10.2459/JCM.0b013e32832b4ccc.
10
Pheochromocytoma. Current concepts in diagnosis, localization, and management.嗜铬细胞瘤。诊断、定位及治疗的当前概念
Prim Care. 1983 Mar;10(1):75-86.

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Pheochromocytoma crisis with cyclic fluctuation in blood pressure mimics acute coronary syndrome.伴有血压周期性波动的嗜铬细胞瘤危象酷似急性冠状动脉综合征。
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Histopathological analysis of spontaneous large necrosis of adrenal pheochromocytoma manifested as acute attacks of alternating hypertension and hypotension: a case report.表现为高血压与低血压交替急性发作的肾上腺嗜铬细胞瘤自发性大片坏死的组织病理学分析:一例报告
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