Sonobe N, Yashima Y, Takahashi Y, Katayose K, Kumashiro H
Department of Neuropsychiatry, Fukushima Medical College, Japan.
Fukushima J Med Sci. 1991 Jun;37(1):29-40.
The present paper reports 3 cases of aphasia with small lesions in the region of the basal ganglia to discuss whether neostrial dysfunction can cause aphasic symptoms. The Standard Language Tests of Aphasia (SLTA) was used to assess the type and degree of aphasia. Two patients with infarction either in the left putamen or in the head of the left caudate nucleus showed severe disturbance only in recalling words, especially nouns. The other patient showed the same symptom, in addition to writing disturbance that developed shortly after surgical extirpation of an arteriovenous malformation (AVM) in the left caudate nuclei. The symptoms common to the 3 patients corresponded well to the "anomic aphasia" proposed by Benson. The aphasic symptoms disappeared completely or largely within several months. This easy reversibility suggests that the aphasic disorder in the three patients was caused by damage not to the basal ganglia themselves, but to the affecting axons passing through or by the nuclei.
本文报告了3例基底神经节区域有小病灶的失语症病例，以探讨新纹状体功能障碍是否会导致失语症状。采用失语症标准语言测试（SLTA）来评估失语症的类型和程度。两名左侧壳核或左侧尾状核头部梗死的患者仅在回忆单词，尤其是名词方面表现出严重障碍。另一名患者除了在左侧尾状核手术切除动静脉畸形（AVM）后不久出现书写障碍外，也表现出相同症状。这3例患者共有的症状与本森提出的“命名性失语症”非常吻合。失语症状在几个月内完全或大部分消失。这种易于逆转表明，这3例患者的失语症并非由基底神经节本身受损所致，而是由穿过这些核团或受其影响的轴突受损所致。
