Yu Ayong, Wang Qinmei, Xue Anquan, Zhu Shuangqian, Wang Shulin, Chen Yunyun, Sun Jin
Affiliated Eye Hospital at Wenzhou Medical College, Wenzhou, China.
Ophthalmologica. 2008;222(1):53-7. doi: 10.1159/000109280. Epub 2007 Dec 19.
To evaluate the effects of angle-supported, iris-fixated and posterior chamber phakic intraocular lens (PIOL) implantation on contrast sensitivity (CS).
This prospective study included 69 eyes of 41 consecutive cases of high myopia which received an angle-supported (Phakic-6H; 26 eyes), iris-fixated (Verisyse; 23 eyes) or posterior chamber PIOL [phakic refractive lens (PRL); 20 eyes]. Photopic, mesopic and mesopic with glare CS were evaluated preoperatively and at least 6 months postoperatively.
In the PRL group, the mean postoperative CS at all frequencies and across all lighting conditions increased. These changes were significant for 6, 12 and 18 cycles per degree (cpd) under both photopic and mesopic conditions (p < 0.01) and for all the tested frequencies under mesopic with glare condition (p < or = 0.01). The average CS was relatively low in the PRL group. These changes were significant for 6 and 12 cpd between the Verisyse and PRL group under photopic condition (p < 0.05), for 3 and 6 cpd under mesopic condition (p < 0.01, p = 0.01) and under mesopic with glare condition (p < 0.01, p < 0.05).
Improvements in postoperative CS confirm that PIOL implantation is a promising alternative for correction of high myopia. In comparison to posterior chamber PIOLs, angle-supported and iris-fixated PIOLs seem to produce a better visual quality in terms of CS, which needs to be warranted by further investigations.
评估前房角支撑型、虹膜固定型及后房型有晶状体眼人工晶状体(PIOL)植入对对比敏感度(CS)的影响。
本前瞻性研究纳入了41例连续的高度近视患者的69只眼,这些患者接受了前房角支撑型(Phakic-6H;26只眼)、虹膜固定型(Verisyse;23只眼)或后房型PIOL [有晶状体眼屈光晶状体(PRL);20只眼]植入。在术前及术后至少6个月评估明视、 mesopic及有眩光的mesopic条件下的对比敏感度。
在PRL组中,所有频率及所有光照条件下术后平均对比敏感度均增加。在明视和mesopic条件下,每度6、12和18周/度(cpd)时这些变化显著(p < 0.01),在有眩光的mesopic条件下所有测试频率时变化显著(p ≤ 0.01)。PRL组的平均对比敏感度相对较低。在明视条件下,Verisyse组和PRL组之间6和12 cpd时这些变化显著(p < 0.05);在mesopic条件下,3和6 cpd时变化显著(p < 0.01,p = 0.01),在有眩光的mesopic条件下变化显著(p < 0.01,p < 0.05)。
术后对比敏感度的改善证实PIOL植入是矫正高度近视的一种有前景的替代方法。与后房型PIOL相比,前房角支撑型和虹膜固定型PIOL在对比敏感度方面似乎能产生更好的视觉质量,这需要进一步研究来证实。