Vasil'ev S A, Efremov E E, Rybachenkova E V, Savenko T V
Ter Arkh. 1991;63(11):82-4.
The authors studied the clinical efficacy of the local external use of fibronectin obtained from autoplasma by heparin cryoprecipitation in 8 patients with immune complex pathology, paraproteinemic hemoblastoses and beta-thalassemia complicated by erosive and ulcerous skin lesions. Autofibronectin was shown to bring about complete healing of ulcerous defects within 10 to 45 days. The therapeutic approach suggested is money-saving and excludes a possibility of transmitting hepatitis B and immunodeficiency viruses by the patient.
作者研究了通过肝素冷沉淀从自身血浆中获取的纤连蛋白局部外用对8例免疫复合物病、副蛋白血症性血液病及合并糜烂性和溃疡性皮肤病变的β地中海贫血患者的临床疗效。结果表明,自身纤连蛋白可在10至45天内使溃疡缺损完全愈合。所建议的治疗方法节省费用,且排除了患者传播乙型肝炎和免疫缺陷病毒的可能性。