一例丙酮酸脱氢酶缺乏所致 Leigh 脑病患者脑 CT 的特征性改变
Characteristic changes on brain CT in a case of Leigh encephalopathy with deficiency of pyruvate dehydrogenase.
作者信息
Arai Y, Miyasato Y, Koide H
机构信息
Division of Child Neurology, Kibou-no-Ie Rehabilitation Center Hospital for the Handicapped, Gunma, Japan.
出版信息
Brain Dev. 1991 Nov;13(6):457-8. doi: 10.1016/s0387-7604(12)80050-7.
PMID:1810165
Abstract
A girl aged 23 months of Leigh encephalopathy with pyruvate dehydrogenase complex (PDHC) deficiency was reported. Brain CT scan showed atrophy of the frontal and parietal cortex, low density in the midbrain and putamina, and rounded caudatum. CT change was showed from rounded to atrophic caudatum during a three-month period. The rounded caudatum may be an early CT finding in Leigh encephalopathy.
摘要
报告了一名23个月大患有 Leigh 脑病且丙酮酸脱氢酶复合物（PDHC）缺乏的女孩。脑部CT扫描显示额叶和顶叶皮质萎缩，中脑和壳核密度减低，尾状核呈圆形。在三个月的时间里，CT表现从尾状核圆形变为萎缩。圆形尾状核可能是Leigh脑病的早期CT表现。
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