Ngai W K, Chang Y Y, Liu J S, Chen S S
Department of Neurology, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Oct;7(10):536-41.
Five cases suffering from unilateral paresthesia over the corner of the mouth and the hand on the same side were examination for cheiro-oral syndrome. Of these, three cases were typical and the other were variant cases associate with transient hemi-signs. Lesion sites were identified by computed tomographic (CT) scan, magnetic resonance imaging (MRI) or both. Of the five patients, lesions were due to thalamic infarction in three cases, pontine hemorrhage in one case, and tumor compression on the right frontoparietal lobe in the last case. The pathophysiology of all cases were classified according to location of the lesion on the thalamus, the pons, and the parietal lobe, which are the usual anatomical sites responsible for this syndrome. Based on the three typical cases and thirteen cases cited from the English literature, a clinical classification has been established. The classification is based on age at the time of onset, gender, lesion site, etiology, risk factors, and certain clinical features. These sixteen cases fell into three distinct groups: a) those in which the thalamic lesions were related to infarction, b) those in which tumors, or in rare cases infarction, were found in the parietal lobe, and c) those in which hemorrhage occurred in the pons. Using this classification, the cheiro-oral syndrome can be more systematically defined.
对5例同侧口角及手部出现单侧感觉异常的患者进行了口手综合征检查。其中，3例为典型病例，另外2例为伴有短暂偏侧体征的变异病例。通过计算机断层扫描（CT）、磁共振成像（MRI）或两者来确定病变部位。5例患者中，3例病变是由丘脑梗死引起，1例是桥脑出血，最后1例是右侧额顶叶肿瘤压迫所致。根据病变位于丘脑、脑桥和顶叶的位置对所有病例的病理生理学进行了分类，这些是导致该综合征的常见解剖部位。基于3例典型病例以及从英文文献中引用的13例病例，建立了一种临床分类方法。该分类基于发病时的年龄、性别、病变部位、病因、危险因素以及某些临床特征。这16例病例分为三个不同的组：a）丘脑病变与梗死相关的病例；b）顶叶发现肿瘤或罕见情况下梗死的病例；c）脑桥出血的病例。使用这种分类方法，可以更系统地定义口手综合征。
