Kadena M, Isomoto S, Tanigawa M, Konoe A, Shimizu A, Fukatani M, Hashiba K
Third Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
Jpn Heart J. 1991 Nov;32(6):759-74. doi: 10.1536/ihj.32.759.
To elucidate differences in conduction properties among the normal atrioventricular (AV) node and the antegrade fast and slow dual AV nodal pathways (DAVNPW), AV nodal conduction curves were analyzed quantitatively in 38 patients. Eighteen patients had antegrade DAVNPW with AV nodal reentrant tachycardia (AVNRT) (dual pathways group) and the remaining 20 had smooth AV nodal conduction curves, without evidence of AV nodal dysfunction (control group). The effective refractory period (ERP) of the antegrade fast pathway was longer than that of the normal AV node (at both basic cycle lengths of 700 and 500 msec, p less than 0.01). Although the atrial premature beats were delayed by a longer ERP in the fast pathway, there was no significant difference in the degree of prolongation of AV nodal conduction time related to shortening of the coupling interval (i.e., ratio of A2H2 increment to A1A2 decrement) between these two pathways. On the other hand, the ERP of the antegrade slow pathway was similar to that of the normal AV node. The degree of prolongation of AV nodal conduction time (relative to the shortening of the coupling interval) was greater in the antegrade slow pathway than in the normal AV node. In conclusion, these findings suggest that in DAVNPW with AVNRT: (1) the antegrade fast pathway is similar to the AV node and its conduction properties are unlikely to be better than those of the normal AV node and (2) the antegrade slow pathway has quantitatively poorer conduction properties than the normal AV node, since it has a greater degree of decremental conduction.
为了阐明正常房室(AV)结与顺行性快、慢双房室结径路(DAVNPW)之间传导特性的差异,对38例患者的房室结传导曲线进行了定量分析。18例患者有顺行性DAVNPW并伴有房室结折返性心动过速(AVNRT)(双径路组),其余20例有平滑的房室结传导曲线,无房室结功能障碍的证据(对照组)。顺行性快径路的有效不应期(ERP)长于正常房室结(在基础周期长度700和500毫秒时均如此,p<0.01)。虽然快径路中房性早搏因ERP延长而延迟,但这两条径路在与耦合间期缩短相关的房室结传导时间延长程度上(即A2H2增量与A1A2减量之比)无显著差异。另一方面,顺行性慢径路的ERP与正常房室结相似。顺行性慢径路中房室结传导时间的延长程度(相对于耦合间期的缩短)大于正常房室结。总之,这些发现提示,在伴有AVNRT的DAVNPW中:(1)顺行性快径路与房室结相似,其传导特性不太可能优于正常房室结;(2)顺行性慢径路的传导特性在数量上比正常房室结差,因为它有更大程度的递减传导。