通过曼尼希反应制备某些哌啶衍生物。 - Suppr

The preparation of some piperidine derivatives by the Mannich reaction.

作者信息

NOLLER C R, BALIAH V

出版信息

J Am Chem Soc. 1948 Nov;70(11):3853-5. doi: 10.1021/ja01191a092.

DOI:10.1021/ja01191a092

PMID:18121891

Abstract

摘要

相似文献

The preparation of some piperidine derivatives by the Mannich reaction.

J Am Chem Soc. 1948 Nov;70(11):3853-5. doi: 10.1021/ja01191a092.

Toxicity of some bis Mannich bases and corresponding piperidinols in the brine shrimp (Artemia salina) bioassay.

J Appl Toxicol. 2003 Jan-Feb;23(1):53-7. doi: 10.1002/jat.887.

Mannich Reactions of Carbohydrate Derivatives with Ketones To Afford Polyoxy-Functionalized Piperidines.

Org Lett. 2019 Feb 15;21(4):1165-1169. doi: 10.1021/acs.orglett.9b00105. Epub 2019 Jan 29.

[On the Mannich reaction of 4-alkoxydesoxybenzoin with piperidine and the grouping of 4-alkylpiperidine to 4-alkoxymethylenedesoxybenzoin].

Arch Pharm Ber Dtsch Pharm Ges. 1960 Sep;293/65:854-64. doi: 10.1002/ardp.19602930908.

Copper-catalyzed Perkin-acyl-Mannich reaction of acetic anhydride with pyridine: expeditious entry to unconventional piperidines.

Org Lett. 2011 Oct 7;13(19):5152-5. doi: 10.1021/ol202027k. Epub 2011 Sep 6.

Mannich-Michael versus formal aza-Diels-Alder approaches to piperidine derivatives.

Org Biomol Chem. 2011 May 7;9(9):3105-21. doi: 10.1039/c0ob00996b. Epub 2011 Mar 9.

Piperidine derivatives. II. Preparation of 2,6-di-(alpha-hydroxybenzyl)-piperidine hydrochloride and related compounds.

J Am Pharm Assoc Am Pharm Assoc. 1950 Aug;39(8):463-5. doi: 10.1002/jps.3030390813.

Piperidine derivatives. I. Preparation of piperidine-2,6-dicarboxylic acid and its N-methyl derivative.

J Am Pharm Assoc Am Pharm Assoc. 1950 Aug;39(8):460-2. doi: 10.1002/jps.3030390811.

Highly enantioselective [4+2] annulation via organocatalytic Mannich-reductive cyclization: one-pot synthesis of functionalized piperidines.

Chem Commun (Camb). 2013 Jun 25;49(50):5645-7. doi: 10.1039/c3cc42431f. Epub 2013 May 20.

Piperidine derivatives; the preparation of l-benzoyl-3-carbethoxy-4-piperidone; a synthesis of guvacine.

J Am Chem Soc. 1946 Jun;68:1049-53. doi: 10.1021/ja01210a040.

引用本文的文献

Synthesis, crystal structure and computational analysis of 2,7-bis-(4-chloro-phen-yl)-3,3-dimethyl-1,4-diazepan-5-one.

Acta Crystallogr E Crystallogr Commun. 2023 Nov 30;79(Pt 12):1212-1217. doi: 10.1107/S2056989023010162. eCollection 2023 Dec 1.

Conformation and vibrational spectroscopic analysis of 2,6-bis(4-fluorophenyl)-3,3-dimethylpiperidin-4-one (BFDP) by DFT method: A potent anti-Parkinson's, anti-lung cancer, and anti-human infectious agent.

Heliyon. 2023 Oct 29;9(11):e21315. doi: 10.1016/j.heliyon.2023.e21315. eCollection 2023 Nov.

Synthesis, crystal structure, stereochemical and Hirshfeld surface analysis of -di-aqua-bis-(1-phenyl-propane-1,2-di-amine-κ,')nickel(II) dichloride dihydrate.

Acta Crystallogr E Crystallogr Commun. 2023 Sep 29;79(Pt 10):967-971. doi: 10.1107/S2056989023008538. eCollection 2023 Oct 1.

Design, docking, and DFT investigations of 2,6-bis(3,4-dihydroxyphenyl)-3-phenethylpiperidin-4-one.

Heliyon. 2021 Feb 11;7(2):e06127. doi: 10.1016/j.heliyon.2021.e06127. eCollection 2021 Feb.

Cytotoxic, larvicidal, nematicidal, and antifeedant activities of piperidin-connected 2-thioxoimidazolidin-4-one derivatives.

Saudi J Biol Sci. 2019 May;26(4):673-680. doi: 10.1016/j.sjbs.2017.12.007. Epub 2017 Dec 24.

Crystal structure and Hirshfeld surface analysis of 3-octyl-4-oxo-2,6-bis-(3,4,5-tri-meth-oxy-phen-yl)piperidinium chloride.

Acta Crystallogr E Crystallogr Commun. 2018 Jun 8;74(Pt 7):931-934. doi: 10.1107/S2056989018008125. eCollection 2018 Jul 1.

Crystal structure of ()-4-benzyl-idene-6-phenyl-1,2,3,4,7,8,9,10-octa-hydro-phenanthridine.

Acta Crystallogr E Crystallogr Commun. 2017 Jun 30;73(Pt 7):1092-1096. doi: 10.1107/S2056989017009537. eCollection 2017 Jul 1.

Synthesis, crystal structures and docking studies of 2,7-diphenyl-1,4-diazepan-5-one derivatives.

Chem Cent J. 2015 Apr 8;9:17. doi: 10.1186/s13065-015-0094-3. eCollection 2015.

Crystal structure of 3-methyl-2,6-bis-(4-methyl-1,3-thia-zol-5-yl)piperidin-4-one.

Acta Crystallogr Sect E Struct Rep Online. 2014 Aug 30;70(Pt 9):o1055. doi: 10.1107/S1600536814018856. eCollection 2014 Sep 1.

3,3,5,5-Tetra-methyl-r-2,c-6-diphenyl-piperidin-4-one.

Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2097. doi: 10.1107/S1600536812018983. Epub 2012 Jun 13.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

The preparation of some piperidine derivatives by the Mannich reaction.

作者信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献