Siegel M A
Department of Oral Medicine and Diagnostic Sciences Dental School, University of Maryland, Baltimore 21201.
Oral Surg Oral Med Oral Pathol. 1991 Dec;72(6):681-4. doi: 10.1016/0030-4220(91)90010-a.
A wedge biopsy technique is described for use when oral manifestations of vesiculoerosive disease are suspected. The resultant soft tissue specimens are submitted for both light microscopic and direct immunofluorescence studies. This technique offers the advantage of obtaining highly diagnostic, mirror-image soft tissue specimens from a single perilesional site while minimizing postsurgical morbidity to the patient.