牙髓复合体的年龄相关变化及其与全身衰老的关系。

Age-related changes of the dental pulp complex and their relationship to systemic aging.

作者信息

Morse D R

机构信息

Department of Endodontology, Temple University School of Dentistry, Philadelphia, PA 19140.

出版信息

Oral Surg Oral Med Oral Pathol. 1991 Dec;72(6):721-45. doi: 10.1016/0030-4220(91)90019-9.

DOI:10.1016/0030-4220(91)90019-9

PMID:1812456

Abstract

The dental pulp and its associated structures, the dentin and the cementum, are discussed. Because many of the age-related pulpal changes have components considered in several of the current theories of aging, these theories are briefly reviewed. Part 2 describes the age-related changes of the dental pulp, the dentin, and the cementum (the dental pulp complex). An attempt is made to differentiate inherent aging changes from physiologic defensive changes and pathologic irritant-induced changes. Part 3 describes the relationship of age-induced changes in the dental pulp complex to components of the current aging theories together with a unified concept of the dental pulp complex aging. Part 4 considers whether dental pulp complex aging can be used as a biomarker for generalized aging. Whether age-related changes of the dental pulp complex can be altered by interventions is discussed.

摘要

本文讨论了牙髓及其相关结构，即牙本质和牙骨质。由于许多与年龄相关的牙髓变化包含在当前几种衰老理论中，因此对这些理论进行了简要回顾。第二部分描述了牙髓、牙本质和牙骨质（牙髓复合体）与年龄相关的变化。试图区分内在的衰老变化、生理防御变化和病理刺激引起的变化。第三部分描述了牙髓复合体中年龄诱导变化与当前衰老理论各组成部分的关系，以及牙髓复合体衰老的统一概念。第四部分探讨了牙髓复合体衰老是否可作为全身衰老的生物标志物。还讨论了牙髓复合体与年龄相关的变化是否可以通过干预来改变。