Bellossi A
Laboratoire de Biophysique, Faculté de Médecine, Rennes, France.
Acta Med Hung. 1991;48(1-2):95-102.
An exposure of adult mice to a pulsed magnetic field (PMF) increases thymus weight. In this work, thymic lymphocytes were studied by cellular electrophoresis because the proliferation and maturation of these cells is linked to an increase in their electrophoretic mobility (EM). Fifteen-week-old female Swiss mice were exposed for 30 min to a 6 mT PMF, 12 or 460 Hz in frequency, according to different modalities. The EM of the thymic cells, suspended in saline were measured from 0 to 96 h after the end of the exposure. For some of the mice the whole body, for others the head only or the body without the head was exposed; the animals were awaken or narcotized, prepared or not with 6-hydroxydopamine. The modifications of the EM are in favour of an action of the PMF on the thymus through the central nervous system.
成年小鼠暴露于脉冲磁场（PMF）会增加胸腺重量。在本研究中，通过细胞电泳对胸腺淋巴细胞进行了研究，因为这些细胞的增殖和成熟与它们电泳迁移率（EM）的增加有关。根据不同方式，将15周龄的雌性瑞士小鼠暴露于频率为12或460Hz、强度为6mT的脉冲磁场中30分钟。在暴露结束后的0至96小时内，测量悬浮在盐水中的胸腺细胞的电泳迁移率。对于一些小鼠，全身暴露；对于另一些小鼠，仅头部或无头身体暴露；动物处于清醒或麻醉状态，用或不用6-羟基多巴胺预处理。电泳迁移率的改变表明脉冲磁场通过中枢神经系统对胸腺产生作用。
