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[采用MOPP/COPP方案(氮芥或环磷酰胺、长春新碱、丙卡巴肼和泼尼松)治疗晚期霍奇金病的远期疗效]

[Late results of the treatment of advanced Hodgkin's disease by the MOPP/COPP programs (chlormethine or cyclophosphamide, vincristine, procarbazine and prednisone)].

作者信息

Błasińska-Morawiec M, Płuzańska A, Krykowski E, Robak T, Mrówka I

机构信息

II Kliniki Chorób Wewnetrznych A.M.

出版信息

Pol Arch Med Wewn. 1991 Oct;86(4):274-80.

PMID:1813880
Abstract

The results of the treatment with MOPP/COPP program for 114 patients with advanced Hodgkin's disease are presented. Complete remission has been achieved in 74 patients (65%). Thirty four of them (30%) are still remaining in first remission. The relapse of disease was observed in 37 patients, in 16 of them during first 24 months of follow-up. Three patients were lost of observation. The analysis of these unsatisfactory long-term results suggests that more effective management policies for patients with advanced Hodgkin's disease are needed.

摘要

本文展示了采用MOPP/COPP方案治疗114例晚期霍奇金病患者的结果。74例患者(65%)实现了完全缓解。其中34例(30%)仍处于首次缓解期。37例患者出现疾病复发,其中16例在随访的前24个月内复发。3例患者失访。对这些不尽人意的长期结果进行分析表明,需要为晚期霍奇金病患者制定更有效的管理策略。

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