Busuioc C, Ionescu V, Murgoci R, Stoicescu A, Ticu M, Velea L, Cristescu D
Chaire d'épidémiologie, Université de Médecine et Pharmacie Carol Davila, Bucarest, Roumanie.
Rev Roum Virol. 1991 Jul-Dec;42(3-4):145-56.
The report presents the peculiar characteristics of influenza epidemics in a big urban centre (B.) of Romania, between 1988 and 1990, surveyed by clinical, epidemiological and laboratory methods. Among the peculiarities of the epidemics: the low rate of endemic morbidity, the seasonal and preseasonal peaks, the very high implication of infantile population in influenza A(H3N2), A(H1N1) and B virus circulation, as well as the high level of mass specific humoral protection against these viruses. Elements of epidemiologic prognosis are suggested for 1991. Opportunity of vaccine prophylaxis using WHO recommended virus strains of the three types: A(H3N2), A(H1N1) and B, for risk groups is discussed.
本报告介绍了1988年至1990年间,通过临床、流行病学和实验室方法对罗马尼亚一个大城市中心(B.)的流感流行特点进行调查的结果。这些流行特点包括:地方发病率低、季节性和季前高峰、婴幼儿人群在甲型(H3N2)、甲型(H1N1)和乙型流感病毒传播中受感染率极高,以及针对这些病毒的群体特异性体液保护水平较高。文中还提出了1991年的流行病学预后因素,并讨论了针对高危人群使用世界卫生组织推荐的三种病毒株(甲型(H3N2)、甲型(H1N1)和乙型)进行疫苗预防的时机。