Vikhlianov I V, Shoĭkhet Ia N, Lazarev A F
Vestn Khir Im I I Grek. 2007;166(5):86-9.
Surgical method of treatment was used in 194 patients with tumors of the mouth cavity and oral part of the pharynx. Combined treatment (radiation therapy and operation in various combinations) was used in 110 of these patients and in 84 patients the treatment was complex (polychemotherapy + operation + postoperative course of radiation therapy). Comparative characterization of operations fulfilled on the initial focus has shown that the number of function-saving operations in the group of patients treated by complex methods was 86.9%, and in the group of patients treated by combined methods it was 70.9%. It can be explained by a higher degree of tumor regression under the influence of neo-adjuvant polychemotherapy than under the action of preoperative course of radiation therapy as well as due to the development of a number of function-saving operations which could be used in patients after a course of neo-adjuvant chemotherapy.