Chiu Shuenn-Nan, Wang Jou-Kou, Wu Mei-Hwan, Chang Chi-Wei, Chen Chun-An, Lin Ming-Tai, Wu En-Ting, Hua Yu Chuan, Lue Hung-Chi
Department of Pediatrics, National Taiwan University Hospital and Medical College, National Taiwan University, Taipei, Taiwan.
J Pediatr. 2008 Jan;152(1):85-9. doi: 10.1016/j.jpeds.2007.05.044. Epub 2007 Oct 24.
To delineate the prevalence and clinical implications of cardiac conduction disturbance (CCD) in school-age children.
Between 1999 and 2001, a citywide survey of 432,166 elementary and high school students had been performed in Taipei by questionnaire, electrocardiography, phonocardiography, and physical examination. Patients with any abnormalities on this survey were referred for final diagnosis.
After excluding those with congenital heart disease (CHD), the prevalence of CCD was 0.75%, higher in males than in females (0.78% vs 0.71%). Incomplete right bundle branch block (IRBBB; 0.32%), complete right bundle branch block (CRBBB; 0.11%), ventricular premature contraction (0.11%), and Wolff-Parkinson-White syndrome (0.067 %) were the most common diagnoses. Second-degree atrioventricular block, IRBBB, CRBBB, and intraventricular conduction delay were more common in males; and atrial premature contraction was more common in females. The prevalence of CCD increased with age, from 0.48% in elementary school students to 0.97% in high school students. After detection of CCD, 39 patients with previously undiagnosed atrial septal defect (ASD) and 15 high-risk patients were found. The sensitivity of IRBBB in screening for ASD was 34.67%.
The prevalence of CCD in children without CHD was 0.75%. Detection of CCD helped identify patients with unrecognized ASD and high-risk cardiac patients.
明确学龄儿童心脏传导障碍(CCD)的患病率及其临床意义。
1999年至2001年期间,台北市通过问卷调查、心电图、心音图和体格检查,对432,166名中小学生进行了全市范围的调查。对此次调查中发现有任何异常的患者进行进一步诊断以明确最终诊断结果。
排除先天性心脏病(CHD)患者后,CCD的患病率为0.75%,男性高于女性(0.78%对0.71%)。不完全性右束支传导阻滞(IRBBB;0.32%)、完全性右束支传导阻滞(CRBBB;0.11%)、室性早搏(0.11%)和预激综合征(0.067%)是最常见的诊断结果。二度房室传导阻滞、IRBBB、CRBBB和室内传导延迟在男性中更为常见;房性早搏在女性中更为常见。CCD的患病率随年龄增长而增加,从小学生中的0.48%增至高中生中的0.97%。在检测到CCD后,发现39例先前未被诊断出的房间隔缺损(ASD)患者和15例高危患者。IRBBB筛查ASD的敏感性为34.67%。
无CHD儿童中CCD的患病率为0.75%。检测CCD有助于识别未被发现的ASD患者和高危心脏病患者。