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基于大样本人群的儿童心律失常和传导障碍患病率

Prevalence of arrhythmias and conduction disturbances in large population-based samples of children.

作者信息

Niwa Koichiro, Warita Naomi, Sunami Yuko, Shimura Akimitsu, Tateno Shigeru, Sugita Katsuo

机构信息

Department of Pediatrics, Chiba Cardiovascular Center, Division of Medicine, Faculty of Education, Chiba University and Chiba Foundation for Health Promotion and Disease Prevention, Ichihara, Chiba, Japan.

出版信息

Cardiol Young. 2004 Feb;14(1):68-74. doi: 10.1017/s104795110400112x.

Abstract

The aim of our study is to provide data on the prevalence of disturbances of rhythm in the general population of children. Accurate estimates of true prevalence of such disturbances of rhythm from large samples are mandatory if we are to interpret properly electrocardiographic abnormalities. We analysed prevalence of disturbances of rhythm in a population of 152,322, comprised of 71,855 elementary school students, 36,692 males and 35,163 females, aged from 5 to 6 years, and 80,467 students of junior high school, 41,842 males and 38,625 females, aged from 12 to 13 years. We analysed the prevalence of premature atrial and ventricular contractions, first, second and third degree atrioventricular block, incomplete and complete right bundle branch block, Wolff-Parkinson-White syndrome, and prolongation of the QT interval. The prevalence of disturbances of rhythm in total rose with age, being found in 1.25% of elementary school students and 2.32% of junior high school students, and was higher in males than females, at 2.00% as opposed to 1.38%, both values being statistically significant at a level of less than 0.0001. Prevalences of all types of rhythmic disturbances were higher in junior high school students than elementary school students (p < 0.0001). Premature atrial and ventricular contractions and prolongation of the QT interval were higher in female than male students, at percentages of 0.089, 0.497, and 0.02 for males, and 0.123, 0.534 and 0.027 in females (p < 0.0001). In contrast, incomplete and complete right bundle branch blocks were higher in males than females, at 0.983% and 0.083% in males versus 0.410% and 0.161% in females (p < 0.0001). Disturbances of rhythm increased with age, and conduction disturbances were higher in male students than female, although premature atrial and ventricular contractions and prolongation of the QT interval were more frequent in female. These data may be useful for future comparative studies of disturbance of rhythm in children.

摘要

我们研究的目的是提供关于儿童普通人群中节律紊乱患病率的数据。如果我们要正确解释心电图异常,就必须从大样本中准确估计此类节律紊乱的真实患病率。我们分析了由152322人组成的人群中的节律紊乱患病率,其中包括71855名小学生,年龄在5至6岁之间,男性36692人,女性35163人;以及80467名初中生,年龄在12至13岁之间,男性41842人,女性38625人。我们分析了房性和室性早搏、一度、二度和三度房室传导阻滞、不完全性和完全性右束支传导阻滞、预激综合征以及QT间期延长的患病率。总体节律紊乱患病率随年龄增长而上升,在小学生中为1.25%,在初中生中为2.32%,男性患病率高于女性,分别为2.00%和1.38%,这两个值在小于0.0001的水平上均具有统计学意义。所有类型节律紊乱的患病率在初中生中均高于小学生(p < 0.0001)。房性和室性早搏以及QT间期延长在女生中高于男生,男生的百分比分别为0.089、0.497和0.02,女生为0.123、0.534和0.027(p < 0.0001)。相比之下,不完全性和完全性右束支传导阻滞在男生中高于女生,男生分别为0.983%和0.083%,女生为0.410%和0.161%(p < 0.0001)。节律紊乱随年龄增加,传导紊乱在男生中高于女生,尽管房性和室性早搏以及QT间期延长在女生中更常见。这些数据可能对未来儿童节律紊乱的比较研究有用。

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