• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一种蒽糖衍生物的合成及用于检测炭疽芽孢的多克隆抗体的制备。

Synthesis of an anthrose derivative and production of polyclonal antibodies for the detection of anthrax spores.

作者信息

Dhénin Sandrine G Y, Moreau Vincent, Morel Nathalie, Nevers Marie-Claire, Volland Hervé, Créminon Christophe, Djedaïni-Pilard Florence

机构信息

Laboratoire des Glucides UMR-CNRS 6219, Institut de Chimie de Picardie, Université de Picardie Jules Verne, 33 rue Saint-Leu, F-80039 Amiens, France.

出版信息

Carbohydr Res. 2008 Aug 11;343(12):2101-10. doi: 10.1016/j.carres.2007.11.030. Epub 2007 Dec 8.

DOI:10.1016/j.carres.2007.11.030
PMID:18155682
Abstract

A straightforward synthesis of a derivative of anthrose, the non-reducing terminal fragment of the antigenic tetrasaccharide from Bacillus anthracis, was achieved starting from d-galactose. This hapten is able to induce a highly specific and sensitive immune response in rabbit when attached to a carrier protein.

摘要

从d-半乳糖出发，实现了炭疽芽孢杆菌抗原性四糖的非还原末端片段——蒽糖衍生物的直接合成。当这种半抗原与载体蛋白相连时，能够在兔体内诱导出高度特异性和灵敏的免疫反应。

相似文献

1
Synthesis of an anthrose derivative and production of polyclonal antibodies for the detection of anthrax spores.一种蒽糖衍生物的合成及用于检测炭疽芽孢的多克隆抗体的制备。
Carbohydr Res. 2008 Aug 11;343(12):2101-10. doi: 10.1016/j.carres.2007.11.030. Epub 2007 Dec 8.
2
Development of antibodies against anthrose tetrasaccharide for specific detection of Bacillus anthracis spores.用于特异性检测炭疽芽孢杆菌孢子的抗蒽糖四糖抗体的研制。
Clin Vaccine Immunol. 2009 Dec;16(12):1728-37. doi: 10.1128/CVI.00235-09. Epub 2009 Sep 30.
3
Immuno-detection of anthrose containing tetrasaccharide in the exosporium of Bacillus anthracis and Bacillus cereus strains.炭疽芽孢杆菌和蜡样芽孢杆菌芽胞外被中含岩藻糖的四糖的免疫检测。
J Appl Microbiol. 2009 May;106(5):1618-28. doi: 10.1111/j.1365-2672.2008.04129.x. Epub 2009 Feb 16.
4
Sensitive and specific enzyme immunoassays for antigenic trisaccharide from Bacillus anthracis spores.用于炭疽芽孢杆菌芽孢抗原三糖的敏感和特异酶免疫分析。
Org Biomol Chem. 2009 Dec 21;7(24):5184-99. doi: 10.1039/b914534f. Epub 2009 Oct 19.
5
The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions.与炭疽芽孢杆菌芽孢相关的保护性抗原（PA）的检测以及抗PA抗体对芽孢萌发和巨噬细胞相互作用的影响。
Microb Pathog. 2005 May-Jun;38(5-6):209-25. doi: 10.1016/j.micpath.2005.02.001. Epub 2005 Apr 22.
6
Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis.不同炭疽杆菌暴发菌株向改变表面寡糖的趋同进化，这些寡糖调节炭疽病的发病机制。
PLoS Biol. 2020 Dec 28;18(12):e3001052. doi: 10.1371/journal.pbio.3001052. eCollection 2020 Dec.
7
Identification of an African Bacillus anthracis lineage that lacks expression of the spore surface-associated anthrose-containing oligosaccharide.鉴定一种缺乏孢子表面相关的含 anthrose 寡糖表达的非洲炭疽杆菌谱系。
J Bacteriol. 2011 Jul;193(14):3506-11. doi: 10.1128/JB.00078-11. Epub 2011 May 13.
8
Anthrax spore detection by a luminex assay based on monoclonal antibodies that recognize anthrose-containing oligosaccharides.基于识别含蒽糖寡糖的单克隆抗体的Luminex检测法检测炭疽芽孢。
Clin Vaccine Immunol. 2010 Sep;17(9):1446-51. doi: 10.1128/CVI.00205-10. Epub 2010 Jul 21.
9
Photogenerated glycan arrays identify immunogenic sugar moieties of Bacillus anthracis exosporium.光生聚糖阵列可识别炭疽芽孢杆菌外孢子的免疫原性糖部分。
Proteomics. 2007 Jan;7(2):180-4. doi: 10.1002/pmic.200600478.
10
Synthesis and antigenic analysis of the BclA glycoprotein oligosaccharide from the Bacillus anthracis exosporium.炭疽芽孢杆菌外孢子囊BclA糖蛋白寡糖的合成与抗原分析
Chemistry. 2006 Dec 13;12(36):9136-49. doi: 10.1002/chem.200601245.

引用本文的文献

1
Development in the Concept of Bacterial Polysaccharide Repeating Unit-Based Antibacterial Conjugate Vaccines.基于细菌多糖重复单元的抗菌结合疫苗概念的发展。
ACS Infect Dis. 2023 Feb 10;9(2):178-212. doi: 10.1021/acsinfecdis.2c00559. Epub 2023 Jan 27.
2
Aroyl and acyl cyanides as orthogonal protecting groups or as building blocks for the synthesis of heterocycles.芳酰基和酰基氰化物作为正交保护基或作为杂环合成的构建块。
Mol Divers. 2019 Nov;23(4):1065-1084. doi: 10.1007/s11030-019-09915-w. Epub 2019 Jan 21.
3
Structure-Immunogenicity Relationship of α- and β-Tetrasaccharide Glycoforms from Exosporium and Fragments Thereof.
α-和β-四糖糖型结构-免疫原性关系来自外孢子及其片段。
Molecules. 2018 Aug 20;23(8):2079. doi: 10.3390/molecules23082079.
4
Glycosylation of BclA Glycoprotein from Bacillus cereus and Bacillus anthracis Exosporium Is Domain-specific.蜡样芽孢杆菌和炭疽芽孢杆菌芽孢外衣BclA糖蛋白的糖基化具有结构域特异性。
J Biol Chem. 2016 Apr 29;291(18):9666-77. doi: 10.1074/jbc.M116.718171. Epub 2016 Feb 26.
5
Development of aptamer beacons for rapid presumptive detection of Bacillus spores.适体生物传感器的研制及其对芽孢杆菌的快速检测
J Fluoresc. 2012 May;22(3):915-24. doi: 10.1007/s10895-011-1030-0. Epub 2012 Jan 5.
6
Identification of an African Bacillus anthracis lineage that lacks expression of the spore surface-associated anthrose-containing oligosaccharide.鉴定一种缺乏孢子表面相关的含 anthrose 寡糖表达的非洲炭疽杆菌谱系。
J Bacteriol. 2011 Jul;193(14):3506-11. doi: 10.1128/JB.00078-11. Epub 2011 May 13.