Burns Stephen F, Miyashita Masashi, Ueda Chihoko, Stensel David J
School of Sport and Exercise Sciences, Longborough University, Longborough, Leicestershire, LE11 3TU, UK.
Int J Sport Nutr Exerc Metab. 2007 Dec;17(6):556-73. doi: 10.1123/ijsnem.17.6.556.
The present study examined how multiple bouts of resistance exercise, performed over 1 d, influence 2 risk factors--postprandial triacylglycerol (TAG) and serum C-reactive-protein (CRP) concentrations--associated with coronary heart disease. Twenty-four men age 23.5 (SD 3.4) y completed two 2-d trials, exercise and control, at least 1 wk apart in a counterbalanced randomized design. On day 1 of the exercise trials participants completed 20 sets of 15 repetitions of 5 different resistance exercises divided into five 45-min bouts of exercise--100 sets and 1500 repetitions in total for all exercises. Exercises were performed at 30-40% of 1-repetition maximum. Blood samples were taken before and after exercise. On day 1 of the control trial participants were inactive, with blood samples taken at time points corresponding to the exercise trial. On day 2 of both trials participants consumed a test meal (0.89 g fat, 1.23 g carbohydrate, 0.4 g protein, 60 kJ per kg body mass). Blood samples were obtained fasted and for 6 h postprandially. Total area under the postprandial TAG concentration versus time curve was 12% lower in the exercise than in the control trial (8.76 [3.54] vs. 9.94 [4.31] mmol.L(-1).6 h-1, respectively; P = 0.037). Serum CRP concentrations did not change over the 2 d in the control trial but increased in the exercise trial: trial x time interaction (P = 0.028). Multiple bouts of resistance exercise reduce postprandial TAG concentrations but increase serum CRP concentrations. The extent to which these findings are clinically relevant requires further study.
本研究探讨了在一天内进行多次抗阻运动如何影响与冠心病相关的两个风险因素——餐后三酰甘油（TAG）和血清C反应蛋白（CRP）浓度。24名年龄为23.5（标准差3.4）岁的男性完成了两项为期2天的试验，即运动试验和对照试验，采用平衡随机设计，间隔至少1周。在运动试验的第1天，参与者完成了5种不同抗阻运动的20组，每组15次重复，分为5个45分钟的运动时段——所有运动总共100组、1500次重复。运动强度为1次重复最大值的30%-40%。在运动前后采集血样。在对照试验的第1天，参与者不进行活动，在与运动试验相对应的时间点采集血样。在两项试验的第2天，参与者食用了一顿测试餐（每千克体重含0.89克脂肪、1.23克碳水化合物、0.4克蛋白质、60千焦）。在空腹和餐后6小时采集血样。运动试验中餐后TAG浓度随时间变化曲线下的总面积比对照试验低12%（分别为8.76[3.54]和9.94[4.31]毫摩尔·升⁻¹·6小时⁻¹；P=0.037）。在对照试验中，血清CRP浓度在2天内没有变化，但在运动试验中有所增加：试验×时间交互作用（P=0.028）。多次抗阻运动可降低餐后TAG浓度，但会增加血清CRP浓度。这些发现与临床相关性的程度需要进一步研究。
