Deng Yong, Zeng Shaoqun, Luo Qingming, Zhang Zhihong, Fu Ling
Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China.
Opt Lett. 2008 Jan 1;33(1):77-9. doi: 10.1364/ol.33.000077.
We investigate numerically the effects of scatterer sizes on backscattered polarization patterns using the third-order scattering model developed. The calculated results show that both parallel and cross polarization patterns from water suspensions of polystyrene spheres have four-lobe structures of the azimuth dependence of intensities. Particularly, the parallel polarization pattern is sensitive to scatterer sizes, exhibiting good agreement with prior experimental measurements. Furthermore, the polarization patterns from the dysplastic and normal cells with different size distribution widths are calculated and analyzed. The results show that the polarization patterns of dysplastic and normal cells have distinct differences, which might be used for identification of the morphological structure changes of cancer, dysplasia, and regeneration cells.
我们使用所开发的三阶散射模型,对散射体尺寸对后向散射偏振图案的影响进行了数值研究。计算结果表明,聚苯乙烯球体水悬浮液的平行偏振图案和交叉偏振图案都具有强度方位角依赖性的四瓣结构。特别地,平行偏振图案对散射体尺寸敏感,与先前的实验测量结果吻合良好。此外,还计算并分析了具有不同尺寸分布宽度的发育异常细胞和正常细胞的偏振图案。结果表明,发育异常细胞和正常细胞的偏振图案存在明显差异,这可能用于识别癌症、发育异常和再生细胞的形态结构变化。