Chen Jun, Yang Xi-li, Zhou Zhao-lun, Li Jian-min, Tan Hai-bin
Department of Cardiology, Foshan First People's Hospital, Foshan 528000, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2007 Dec;27(12):1927-8.
To assess the value of routine intra-aortic balloon pump (IABP) support in patients with high-risk acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI).
The clinical data of 41 patients with high-risk AMI undergoing emergency PCI with routine IABP support were retrospectively reviewed, and 38 patients paired with the former group receiving emergency PCI for high-risk AMI without IABP support at the same time were included as the control group. Thirty days after the operation, the two groups were compared for myocardial ischemic events, left ventricular function and major adverse cardiac events (MACE).
Patients receiving IABP support had a significantly lower incidence of myocardial ischemic events than those without IABP (4.9% vs 15.8%, P<0.05), and showed greater improvement in the left ventricular function. Significant differences were also observed in the mortality rate, incidence of reinfarction and revascularization rate between the two groups, but not in the rate of MACE.
Patients undergoing PCI for high-risk acute AMI can benefit from routine IABP support in terms of improvement of left ventricular function and reduce myocardial ischemic events and the rate of MACE. These results, however, still await further confirmation by large-scale clinical trials.
评估常规主动脉内球囊反搏（IABP）支持在接受经皮冠状动脉介入治疗（PCI）的高危急性心肌梗死（AMI）患者中的价值。
回顾性分析41例接受常规IABP支持的高危AMI患者急诊PCI的临床资料，并纳入38例同时接受高危AMI急诊PCI但未使用IABP支持的患者作为对照组。术后30天，比较两组的心肌缺血事件、左心室功能和主要不良心脏事件（MACE）。
接受IABP支持的患者心肌缺血事件发生率显著低于未接受IABP支持的患者（4.9%对15.8%，P<0.05），且左心室功能改善更明显。两组在死亡率、再梗死发生率和血管重建率方面也存在显著差异，但在MACE发生率方面无差异。
接受高危急性AMI PCI的患者在改善左心室功能、减少心肌缺血事件和MACE发生率方面可从常规IABP支持中获益。然而，这些结果仍有待大规模临床试验进一步证实。
