性激素水平与勃起功能障碍的关系：常规应进行哪些检查？

A relationship of sex hormone levels and erectile dysfunction: which tests should be done routinely?

作者信息

Müezzinoğu Talha, Gümüş Bilal, Temeltaş Gökhan, Ari Zeki, Büyüksu Coşkun

机构信息

Department of Urology, Celal Bayar University, Medical Faculty, 45010 Manisa, Turkey.

出版信息

Yonsei Med J. 2007 Dec 31;48(6):1015-9. doi: 10.3349/ymj.2007.48.6.1015.

DOI:10.3349/ymj.2007.48.6.1015

PMID:18159595

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2628192/

Abstract

PURPOSE

In this study, the relationship between sex hormone levels and erectile dysfunction (ED), as well as the necessity of routinely measuring sex hormone levels were evaluated.

MATERIALS AND METHODS

This study included one hundred patients admitted to a urology clinic for sexual dysfunction. To determine the hormone levels, following the history (included IIEF-5 score) and physical examination, triple blood samples were collected at intervals of 15 minutes between 08:00 and 10:00 am. Total and free testosterone, prolactin, follicle stimulating hormone and luteinizing hormone levels were studied.

RESULTS

Mean age was 43 (23-80) years. IIEF-5 score was less than 21 [9.8-4.3 (3-19)] in all study groups. There was a statistically significant correlation between tT and FSH, as well as between LH and FSH in Pearson (r =-0.513, p < 0.001, respectively) and also in Spearman tests (r=-0.224, p=0.042 and r=-0.459, p < 0.001, respectively). However, there was no correlation between age and serum hormone levels (p > 0.05). Of the 100 patients, 18 (18%) had low tT, 77 (77%) had normal and 5 (5%) had high tT levels. No statistically significant correlation was found between decreased libido and tT levels (p > 0.05). Twelve (66.6%) of the 18 patients with low tT had normal libido.

CONCLUSION

Analyzing the medical history in detail and performing a thorough physical examination can reduce the need for excessive studies and consultations, and enables patients to save time and costs.

摘要

目的

本研究评估性激素水平与勃起功能障碍（ED）之间的关系，以及常规检测性激素水平的必要性。

材料与方法

本研究纳入了100名因性功能障碍入住泌尿外科门诊的患者。为测定激素水平，在采集病史（包括国际勃起功能指数-5评分）和进行体格检查后，于上午8点至10点之间每隔15分钟采集三份血样。研究了总睾酮和游离睾酮、催乳素、促卵泡生成素和促黄体生成素水平。

结果

平均年龄为43（23 - 80）岁。所有研究组的国际勃起功能指数-5评分均低于21[9.8 - 4.3（3 - 19）]。在Pearson检验中，总睾酮与促卵泡生成素之间以及促黄体生成素与促卵泡生成素之间存在统计学显著相关性（r分别为 - 0.513，p < 0.001），在Spearman检验中也存在相关性（r分别为 - 0.224，p = 0.042和r = - 0.459，p < 0.001）。然而，年龄与血清激素水平之间无相关性（p > 0.05）。100名患者中，18例（18%）总睾酮水平低，77例（77%）正常，5例（5%）高。性欲减退与总睾酮水平之间未发现统计学显著相关性（p > 0.05）。18例总睾酮水平低的患者中有12例（66.6%）性欲正常。