Charoenkwan Kittipat, Pranpanas Savitree
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang, Mai University, Chiang Mai 50200, Thailand.
Asian Pac J Cancer Prev. 2007 Jul-Sep;8(3):387-9.
Although effective as a primary treatment for early-stage cervical cancer, radical hysterectomy is associated with significant long-term morbidities, most commonly, voiding dysfunction.
To examine prevalence and characteristics of voiding dysfunction following radical hysterectomy for early-stage cervical cancer.
One hundred-eighty seven patients with FIGO stage IA2-IIA cervical cancer who underwent class II-III radical hysterectomy with systematic pelvic lymphadenectomy between January 1, 2002 and June 31, 2005 were interviewed with questionnaire on voiding function. Medical records were also reviewed for operative and pathologic data.
The prevalence of symptomatic bladder dysfunction was 25.1%. There was no statistically significant association between rates of bladder dysfunction and all examined clinical/operative factors. The most common pattern of bladder dysfunction were incomplete emptying in 25 (13.4%) and urgency and nocturia in 21 (11.2%) each.
Voiding dysfunction is a common and clinically significant long-term complication following radical hysterectomy. The pattern of dysfunction reflects combined surgical disruption of both parasympathetic and sympathetic innervations of the pelvis.
根治性子宫切除术虽然是早期宫颈癌的有效主要治疗方法，但会导致显著的长期并发症，最常见的是排尿功能障碍。
研究早期宫颈癌根治性子宫切除术后排尿功能障碍的患病率及特征。
对2002年1月1日至2005年6月31日期间接受II - III类根治性子宫切除术及系统性盆腔淋巴结清扫术的187例国际妇产科联盟（FIGO）IA2 - IIA期宫颈癌患者进行了排尿功能问卷调查。还查阅了手术和病理资料的医疗记录。
有症状的膀胱功能障碍患病率为25.1%。膀胱功能障碍发生率与所有检查的临床/手术因素之间无统计学显著关联。膀胱功能障碍最常见的类型是排尿不完全，有25例（13.4%），尿急和夜尿各有21例（11.2%）。
排尿功能障碍是根治性子宫切除术后常见且具有临床意义的长期并发症。功能障碍模式反映了盆腔副交感神经和交感神经支配的联合手术破坏。
