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发展中国家的艾滋病病毒自愿咨询检测及行为风险降低:一项1990 - 2005年的荟萃分析

HIV voluntary counseling and testing and behavioral risk reduction in developing countries: a meta-analysis, 1990--2005.

作者信息

Denison Julie A, O'Reilly Kevin R, Schmid George P, Kennedy Caitlin E, Sweat Michael D

机构信息

Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.

出版信息

AIDS Behav. 2008 May;12(3):363-73. doi: 10.1007/s10461-007-9349-x. Epub 2007 Dec 27.

Abstract

The effectiveness of HIV voluntary counseling and testing (VCT) in reducing HIV risk behaviors in developing countries was assessed using meta-analytic methods. A standardized protocol was used for searching, acquiring, and extracting study data and meta-analyzing the results. Seven studies met the inclusion criteria. VCT recipients were significantly less likely to engage in unprotected sex when compared to behaviors before receiving VCT, or as compared to participants who had not received VCT [OR 1.69; 95%CI 1.25-2.31]. VCT had no significant effect on the number of sex partners [OR 1.22; 95%CI 0.89-1.67]. While these findings provide only moderate evidence in support of VCT as an effective prevention strategy, neither do they negate the need to expand access to HIV testing and counseling services. Such expansion, however, must be accompanied by rigorous evaluation in order to test, refine and maximize the preventive benefits of learning one's HIV infection status through HIV testing and counseling.

摘要

采用荟萃分析方法评估了在发展中国家开展的艾滋病病毒自愿咨询和检测(VCT)在降低艾滋病病毒风险行为方面的效果。使用标准化方案检索、获取和提取研究数据,并对结果进行荟萃分析。七项研究符合纳入标准。与接受VCT之前的行为相比,或与未接受VCT的参与者相比,接受VCT的人进行无保护性行为的可能性显著降低[比值比(OR)为1.69;95%置信区间(CI)为1.25 - 2.31]。VCT对性伴侣数量没有显著影响[OR为1.22;95%CI为0.89 - 1.67]。虽然这些研究结果仅提供了适度的证据支持VCT作为一种有效的预防策略,但它们也并未否定扩大艾滋病病毒检测和咨询服务可及性的必要性。然而,这种扩大必须伴随严格的评估,以便通过艾滋病病毒检测和咨询来检验、完善并最大化了解自身艾滋病病毒感染状况所带来的预防益处。

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