Race Amos, Mann Kenneth A
Musculoskeletal Science Research Center, Institute for Human Performance, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
J Biomed Mater Res B Appl Biomater. 2008 Jul;86(1):278-82. doi: 10.1002/jbm.b.31016.
Cement mantles around metallic implants have pre-existing flaws (shrinkage induced cracks, laminations, and endosteal surface features) and their fatigue failure is related to the fatigue crack propagation (FCP) rate of bone cement. We estimated the relevant in vivo range of cyclic stress intensity factor (DeltaK) around a generic femoral stem (0-1 MPa square root(m)) and determined that previous FCP data did not adequately cover this range of DeltaK. Vacuum-mixed standard bone cement was machined into ASTM E647 standard compact notched tension specimens. These were subject to sinusoidal loading (R = 0.1) at 5 Hz in 37 degrees C DI water, covering a DeltaK range of 0.25-1.5 MPa square root(m) (including a decreasing DeltaK protocol). FCP-rate data is normally reduced to a power-law fit relating crack growth rate (da/dn) to DeltaK. However, a substantial discontinuity was observed in our data at around DeltaK = 1, so two power-law fits were used. Over the physiologically plausible range of DeltaK, cracks grew at a rate of 2.9 E -8 x DeltaK(2.6) m/cycle. Our data indicated that FCP-rates for 0.5 > DeltaK > 0.3 MPa square root(m) are between 10 E -8 and 10 E -8 m/cycle, 1 or 2 orders of magnitude greater than predicted by extrapolating from previous models based on higher DeltaK data.
金属植入物周围的骨水泥套存在预先存在的缺陷(收缩引起的裂纹、分层和骨内膜表面特征),其疲劳失效与骨水泥的疲劳裂纹扩展(FCP)速率有关。我们估计了一个通用股骨柄周围循环应力强度因子(ΔK)的体内相关范围(0-1兆帕平方根(米)),并确定先前的FCP数据没有充分覆盖这个ΔK范围。将真空混合的标准骨水泥加工成ASTM E647标准紧凑缺口拉伸试样。这些试样在37摄氏度的去离子水中以5赫兹的频率承受正弦加载(R = 0.1),覆盖的ΔK范围为0.25-1.5兆帕平方根(米)(包括一个ΔK递减方案)。FCP速率数据通常简化为将裂纹扩展速率(da/dn)与ΔK相关联的幂律拟合。然而,在我们的数据中,在ΔK约为1时观察到了明显的不连续性,因此使用了两个幂律拟合。在生理上合理的ΔK范围内,裂纹以2.9×10^-8×ΔK^(2.6)米/循环的速率扩展。我们的数据表明,对于0.5>ΔK>0.3兆帕平方根(米),FCP速率在10×10^-8至10×10^-8米/循环之间,比根据先前基于更高ΔK数据的模型外推预测的速率大1或2个数量级。