自体干细胞移植后儿童的结节性肺病变：一个误解来源

Nodular pulmonary lesions in children after autologous stem cell transplantation: a source of misinterpretation.

作者信息

Fazekas Tamas, Wiesbauer Peter, Kronberger Martina, Wank Hans, Gadner Helmut, Dworzak Michael

机构信息

St. Anna Children's Hospital, Vienna, Austria.

出版信息

Br J Haematol. 2008 Feb;140(4):429-32. doi: 10.1111/j.1365-2141.2007.06951.x. Epub 2007 Dec 19.

DOI:10.1111/j.1365-2141.2007.06951.x

PMID:18162118

Abstract

In children with malignant disorders, autologous haematopoietic stem cell transplantation (HSCT) represents a therapeutic option, but several possible complications, such as life-threatening pulmonary disease, make appropriate diagnostic procedures essential. We describe two cases with bronchiolitis obliterans with organizing pneumonia after HSCT, with a brief review of important differential diagnoses.

摘要

在患有恶性疾病的儿童中，自体造血干细胞移植（HSCT）是一种治疗选择，但一些可能的并发症，如危及生命的肺部疾病，使得适当的诊断程序至关重要。我们描述了两例HSCT后发生闭塞性细支气管炎伴机化性肺炎的病例，并简要回顾了重要的鉴别诊断。