Safwat Ahmed S, Bissada Nabil K
Department of Urology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205-7199, USA.
Can J Urol. 2007 Dec;14(6):3757-60.
Pheochromocytoma of the urinary bladder is rare. Herein, we report our experience with pheochromocytoma of the urinary bladder in three patients.
Records of three consecutive patients diagnosed with bladder pheochromocytoma were reviewed. Patients' age, sex, presentation, associated conditions, diagnostic and imaging modalities utilized, management and follow up were recorded.
The three patients included one child and two adults. An 11-year-old female presented with hematuria and bladder mass. Transurethral biopsy was non-diagnostic and she underwent partial cystectomy with eventual diagnosis of pheochromocytoma. Of the two adults, one was a 35-year-old female with history of gestational tumor who was being followed with computed tomography (CT) scan. A bladder mass was incidentally discovered. Transurethral resection of bladder tumor revealed pheochromocytoma and she underwent partial cystectomy. In retrospect, she has had symptoms related to micturition. The third patient is a 32-year-old male, who presented with fainting on voiding which suggested pheochromocytoma. He was also managed with partial cystectomy. There were no perioperative complications in any of the three patients.
Pheochromocytoma of the urinary bladder has unique characteristics. A high index of suspicion should be present in patients who present with suggestive symptoms associated with voiding. In this series, all patients were successfully managed with partial cystectomy.
膀胱嗜铬细胞瘤较为罕见。在此,我们报告三例膀胱嗜铬细胞瘤患者的诊治经验。
回顾性分析连续诊断为膀胱嗜铬细胞瘤的三例患者的病历资料。记录患者的年龄、性别、临床表现、相关疾病、所采用的诊断及影像学检查方法、治疗及随访情况。
三例患者中,一例为儿童,两例为成人。一名11岁女性因血尿及膀胱肿块就诊。经尿道活检未能明确诊断,遂行膀胱部分切除术,最终确诊为嗜铬细胞瘤。两名成人患者中,一名35岁女性有妊娠肿瘤病史,一直在接受计算机断层扫描(CT)检查。偶然发现膀胱肿块。经尿道膀胱肿瘤切除术显示为嗜铬细胞瘤,随后她接受了膀胱部分切除术。回顾病史,她曾有与排尿相关的症状。第三位患者是一名32岁男性,因排尿时晕厥提示嗜铬细胞瘤。他也接受了膀胱部分切除术。三例患者均未出现围手术期并发症。
膀胱嗜铬细胞瘤具有独特的特征。对于出现与排尿相关提示性症状的患者,应高度怀疑此病。在本系列病例中,所有患者均通过膀胱部分切除术成功治疗。