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森宁手术(Senning operation)后的再次手术发生率及结果:单中心314例患者27年的随访情况

Incidence and results of reoperations following the Senning operation: 27 years of follow-up in 314 patients at a single center.

作者信息

Hörer Jürgen, Karl Elisabeth, Theodoratou Georgia, Schreiber Christian, Cleuziou Julie, Prodan Zsolt, Vogt Manfred, Lange Rüdiger

机构信息

Department of Cardiovascular Surgery, German Heart Center Munich at the Technical University, Lazarettstr. 36, D-80636 Munich, Germany.

出版信息

Eur J Cardiothorac Surg. 2008 Jun;33(6):1061-7; discussion 1067-8. doi: 10.1016/j.ejcts.2007.11.012. Epub 2008 Mar 4.

Abstract

OBJECTIVES

Atrial switch procedures for transposition of the great arteries are associated with reoperations mainly for systemic ventricular dysfunction and baffle complications. This study aims at identifying the results of reoperations following the Senning operation.

METHODS

Records of 314 hospital survivors who had undergone the Senning operation were reviewed for details concerning cardiac reoperations.

RESULTS

Reoperations were required in 32 patients (systemic ventricular failure n=12, baffle complications n=11, left ventricular outflow tract obstruction n=7, aortic coarctation n=2) during a mean follow-up time of 18.2+/-5.7 years. Freedom from reoperation and survival at 25 years was 88.0+/-2.1% and 90.9+/-2.3%, respectively. Among patients who underwent reoperation for systemic ventricular failure (arterial switch and Senning take-down without prior pulmonary artery banding n=2, with prior banding n=3, banding without conversion n=4, tricuspid valve repair n=3), two patients died at the time of arterial switch and Senning take-down, and two patients died 4 and 16 months after tricuspid valve repair, respectively. Mean follow-up time after the first reoperation was 7.7+/-5.9 years. Survival after reoperation for systemic ventricular failure at 30 days, 1 year, and 10 years, was 91.7+/-8.0%, 83.3+/-10.8%, and 64.8+/-14.3%, respectively. Survival after reoperation for baffle complications and left ventricular outflow tract obstruction at 10 years was 85.7+/-13.2% and 83.3+/-15.2%, respectively.

CONCLUSIONS

Reoperations following the Senning operation are rare. Reoperations for baffle complications or left ventricular outflow tract obstruction can be performed with good results in the mid-term. However, reoperations for systemic ventricular failure are demanding, and are associated with a high operative and mid-term mortality.

摘要

目的

大动脉转位的心房调转手术与再次手术相关,主要原因是体循环心室功能障碍和挡板并发症。本研究旨在确定森宁手术后再次手术的结果。

方法

回顾了314例接受森宁手术的住院幸存者的记录,以获取有关心脏再次手术的详细信息。

结果

在平均随访时间18.2±5.7年期间,32例患者需要再次手术(体循环心室衰竭n = 12,挡板并发症n = 11,左心室流出道梗阻n = 7,主动脉缩窄n = 2)。25年时免于再次手术和生存的比例分别为88.0±2.1%和90.9±2.3%。在因体循环心室衰竭接受再次手术的患者中(未预先进行肺动脉环扎的动脉调转和森宁拆除术n = 2,预先进行环扎的n = 3,未进行转换的环扎术n = 4,三尖瓣修复术n = 3),2例患者在动脉调转和森宁拆除术时死亡,2例患者分别在三尖瓣修复术后4个月和16个月死亡。首次再次手术后的平均随访时间为7.7±5.9年。因体循环心室衰竭再次手术后30天、1年和10年的生存率分别为91.7±8.0%、83.3±10.8%和64.8±14.3%。因挡板并发症和左心室流出道梗阻再次手术后10年的生存率分别为85.7±13.2%和83.3±15.2%。

结论

森宁手术后再次手术很少见。因挡板并发症或左心室流出道梗阻进行的再次手术在中期可取得良好效果。然而,因体循环心室衰竭进行的再次手术要求高,且手术死亡率和中期死亡率都很高。

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