[The effect of Cu, Zn, Mn, on selenium content in the liver, brain, blood and kidney of mice].

The influence of dietary copper, zinc and manganese on the contents of selenium in liver, brain, and kidney of 150 mice was studied. The mice were divided into 5 groups with different trace elements in their forage (I. 40ppm Cu+4ppm Se, II. 100ppm Zn+4PPm Se, III. 4ppm Mn+4ppm Se, IV. control group). Every 10 mice were killed at one month intervals in each group and the contents of selenium in liver, brain, kidney and blood were determined. The selenium contents of blood, kidney in I, II groups were significantly lower than in IV group. The selenium content of liver was also significantly lower than IV group in two months, but no difference in the third month. No change of selenium content in brain had been observed.