Flores-de-Jacoby L
Universitätsklinik Marburg, Abteilung für Parodontologie.
Dtsch Zahnarztl Z. 1991 Jun;46(6):390-3.
Results of studies on animal models have shown that only guided periodontal tissue regeneration (GTR) will induce growth of new connective tissue fibers attached to new zement and bone tissue when the root surface had been exposed to plaque or pocket organisms. Studies of various authors suggest that it is exclusively the progenitor cells in the still existing periodontal ligament that permit regeneration. The development of GTR is based on biological principles. In the beginning its application was limited to periodontal surgery and has meanwhile expanded to include other areas such as implantology and oral surgery. Best results can be achieved in the periodontological treatment of three-walled bone defects and class II furcation involvements according to the data of several studies.
对动物模型的研究结果表明，当根面暴露于菌斑或牙周袋微生物时，只有引导性牙周组织再生（GTR）能诱导附着于新牙骨质和骨组织的新结缔组织纤维生长。不同作者的研究表明，正是现存牙周膜中的祖细胞实现了再生。GTR的发展基于生物学原理。起初，它仅应用于牙周手术，如今已扩展到包括种植学和口腔外科等其他领域。根据多项研究数据，在三壁骨缺损和II度根分叉病变的牙周治疗中可取得最佳效果。
