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Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities.

作者信息

Trendelenburg U, Russ H, Schömig E

机构信息

Department of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany.

出版信息

J Neural Transm Suppl. 1991;34:19-25. doi: 10.1007/978-3-7091-9175-0_3.

DOI:10.1007/978-3-7091-9175-0_3
PMID:1817160
Abstract

The combination of hypoxia plus glucose deprivation or of hypoxia plus lactate induces carrier-mediated outward transport of 3H-noradrenaline in the rat vas deferens. Lactate efflux is higher from atria than from vas deferens. Hence, the much lower contribution by outward transport to the spontaneous efflux of 3H-noradrenaline in vas deferens than atria is likely to be due to a better supply of oxygen (and perhaps also glucose) to the 3H-noradrenaline-storing varicosities in vas deferens than in atria.

摘要

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