小鼠的刻板行为和不对称性。

Stereotypy and asymmetry in mice.

作者信息

Dews P B

机构信息

Laboratory of Psychobiology, Harvard Medical School, Boston, MA.

出版信息

J Neural Transm Suppl. 1991;34:211-6. doi: 10.1007/978-3-7091-9175-0_27.

DOI:10.1007/978-3-7091-9175-0_27

PMID:1817161

Abstract

Mice ran in a circular runway. Number and direction of circuits were recorded. Most control mice ran about the same number of circuits in each direction. After 100 mumols/kg cocaine there were 3.5 times as many circuits and most mice ran most circuits in one direction. Some mice ran strongly in one direction after a first dose of cocaine and strongly in the other direction after a second dose. Hence, the primary influence toward unidirectional running is stereotypy rather than asymmetry.

摘要

小鼠在圆形跑道上奔跑。记录其奔跑的圈数和方向。大多数对照小鼠在每个方向上奔跑的圈数大致相同。给予100微摩尔/千克可卡因后，圈数增加了3.5倍，且大多数小鼠在一个方向上奔跑的圈数最多。一些小鼠在首次注射可卡因后向一个方向强烈奔跑，在第二次注射后则向另一个方向强烈奔跑。因此，对单向奔跑的主要影响是刻板行为而非不对称性。