Kim Sang Gi, Jung Min Kyu, Jeon Seong Woo, Cho Chang Min, Tak Won Young, Kweon Young Oh, Kim Sung Kook, Choi Yong Hwan
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Korean J Gastroenterol. 2007 Jul;50(1):61-5.
Epithelioid hemangioendothelioma is a rare vascular origin tumor which usually occurs in soft tissues, liver, and lung. It usually affects adult women and presents as multiple hepatic nodules with mainly peripheral distribution. It is difficult to diagnose and treat because of non-specific clinical manifestations and findings on the imaging study. Moreover, pathological misdiagnosis is common. We report a case of this rare tumor that was detected incidentally. Final diagnosis was based on histological evidence. A 52-years old man suffered from right upper quadrant abdominal pain for 3 months, and was initially misdiagnosed as a metastatic carcinoma. Physical examination revealed superior cervical lymphadenopathy with mild hepatomegaly. Finally, hepatic epithelioid hemangioendothelioma was diagnosed on the basis of positive immunohistochemical staining for factor VIII, CD34, and VEGF. Our case highlights the importance of a histological diagnosis to avoid misdiagnosis.
上皮样血管内皮瘤是一种罕见的起源于血管的肿瘤，通常发生于软组织、肝脏和肺。它通常影响成年女性，表现为多个主要分布于周边的肝结节。由于临床表现不特异以及影像学检查结果，其诊断和治疗都很困难。此外，病理误诊很常见。我们报告一例偶然发现的这种罕见肿瘤病例。最终诊断基于组织学证据。一名52岁男性右上腹疼痛3个月，最初被误诊为转移性癌。体格检查发现颈上淋巴结肿大伴轻度肝肿大。最终，基于因子VIII、CD34和VEGF免疫组化染色阳性诊断为肝上皮样血管内皮瘤。我们的病例强调了组织学诊断以避免误诊的重要性。
