Woelfle J
Zentrum für Kinderheilkunde der Universität Bonn, Germany.
Klin Padiatr. 2008 Jan-Feb;220(1):10-5. doi: 10.1055/s-2007-971046.
Five to ten percent of all children are born small for gestational age (SGA). SGA children are not only at risk of remaining small as an adult in case of lacking catch-up growth, but may develop several metabolic disturbances which might have a serious impact on the future health of these children. In this context, several studies described abnormalities of the pubertal development in SGA children, especially in SGA children demonstrating rapid postnatal weight gain. This review highlights the current knowledge of the relationship between auxiological birth para-meters and subsequent pubertal course, and the interrelationships between puberty and growth in SGA children with and without growth hormone therapy.
所有儿童中有5%至10%出生时为小于胎龄儿（SGA）。小于胎龄儿若没有出现追赶性生长，不仅有成年后身材仍矮小的风险，还可能出现多种代谢紊乱，这可能会对这些儿童未来的健康产生严重影响。在这种情况下，多项研究描述了小于胎龄儿青春期发育的异常情况，尤其是出生后体重快速增加的小于胎龄儿。本综述重点介绍了目前关于人体测量学出生参数与后续青春期进程之间关系的知识，以及接受和未接受生长激素治疗的小于胎龄儿青春期与生长之间的相互关系。
