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[每周透析联合低蛋白饮食和必需氨基酸。初步数据]

[Weekly dialysis integrated with low-protein diet and essential amino acids. Preliminary data].

作者信息

Cardelli R, D'Amicone M, Manzione A, Gurioli L, Grott G, Biselli L, Priasca G, Agagliati D

机构信息

Servizio di Nefrologia e Dialisi, Ospedale Maggiore di Chieri, Torino.

出版信息

Minerva Urol Nefrol. 1991 Jul-Sep;43(3):211-6.

PMID:1817346
Abstract

The possibility of applying a once-a-week dialysis programme supplemented with hypoproteic diet as an adequate technique for starting the uraemic patient on dialysis is examined. Thirteen patients have been so treated, 7 of them currently under treatment for a global period of observation of 46 months. At the moment dialysis began, mean glomerular filtrate was 5.14 ml/min. Once-a-week dialytic treatment with bicarbonate dialysis was associated with a hypoproteic diet of 0.5 g/kg/die of proteins, supplemented with essential amino acids. This treatment showed excellent dialytic tolerance, the values of dialysis start blood nitrogen were lower than 200 mg/dl and dialytic efficiency was compatible with a Kt/v greater than 1.1. There was no observation of any subjective or objective symptomatology that could be related to dialytic inadequacy. Taken as a whole these results make it possible to state that this type of approach permits a gradual start to dialysis and deserves further study.

摘要

研究了采用每周一次的透析方案并辅以低蛋白饮食作为让尿毒症患者开始透析的适当技术的可能性。13名患者接受了这种治疗,其中7名患者目前正在接受治疗,总观察期为46个月。在开始透析时,平均肾小球滤过率为5.14毫升/分钟。每周一次的碳酸氢盐透析治疗与0.5克/千克/天蛋白质的低蛋白饮食相关,并补充必需氨基酸。这种治疗显示出极佳的透析耐受性,透析开始时的血氮值低于200毫克/分升,透析效率与大于1.1的Kt/v值相符。未观察到任何可能与透析不充分相关的主观或客观症状。总体而言,这些结果表明这种方法能够使透析逐步开始,值得进一步研究。

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