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斜坡垂体腺瘤伴肢端肥大症:病例报告及文献复习

Clival pituitary adenoma with acromegaly: case report and review of literature.

作者信息

Bhatoe Harjinder S, Kotwal Narendra, Badwal Sonia

机构信息

Department of Neurosurgery, Army Hospital (Research & Referral), Delhi Cantt, New Delhi, India.

出版信息

Skull Base. 2007 Jul;17(4):265-8. doi: 10.1055/s-2007-985195.

Abstract

The pituitary develops as a result of complex, intricate, and precise neuro-embryological events in the sixth to eighth weeks of gestation. Some ectopic cell rests can become adenomatous. Rarely, these cell rests in the clivus can be the site of formation of adenoma. Our patient, a 35-year-old parous woman, was being treated for acromegaly, and imaging studies revealed a clival mass lesion. Trans-sphenoidal excision was done and immunohistochemistry revealed the tumor to be a growth hormone-secreting tumor.

摘要

垂体是在妊娠第六至八周期间复杂、精细且精确的神经胚胎学事件的结果下发育而成。一些异位细胞残余可发展为腺瘤。罕见的是,斜坡处的这些细胞残余可能是腺瘤形成的部位。我们的患者是一名35岁经产妇,因肢端肥大症接受治疗,影像学检查发现斜坡有占位性病变。进行了经蝶窦切除术,免疫组化显示该肿瘤为分泌生长激素的肿瘤。

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本文引用的文献

1
Ectopic clival craniopharyngioma.异位斜坡颅咽管瘤。
Acta Neurochir (Wien). 2002 Nov;144(11):1221-4. doi: 10.1007/s00701-002-1022-6.
5
Infiltrative clival pituitary adenoma of ectopic origin.异位起源的浸润性斜坡垂体腺瘤。
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Pituitary adenoma as an unsuspected clival tumor.垂体腺瘤作为一种未被怀疑的斜坡肿瘤。
Am J Surg Pathol. 1995 Aug;19(8):900-3. doi: 10.1097/00000478-199508000-00004.
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Extrasellar adenohypophyseal tissue in the female.
Australas Radiol. 1970 Aug;14(3):241-7. doi: 10.1111/j.1440-1673.1970.tb01624.x.
10
Ectopic prolactinoma within the sphenoid sinus.蝶窦内异位催乳素瘤。
Neurosurgery. 1989 Feb;24(2):279-82. doi: 10.1227/00006123-198902000-00022.

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