Bhatoe Harjinder S, Kotwal Narendra, Badwal Sonia
Department of Neurosurgery, Army Hospital (Research & Referral), Delhi Cantt, New Delhi, India.
Skull Base. 2007 Jul;17(4):265-8. doi: 10.1055/s-2007-985195.
The pituitary develops as a result of complex, intricate, and precise neuro-embryological events in the sixth to eighth weeks of gestation. Some ectopic cell rests can become adenomatous. Rarely, these cell rests in the clivus can be the site of formation of adenoma. Our patient, a 35-year-old parous woman, was being treated for acromegaly, and imaging studies revealed a clival mass lesion. Trans-sphenoidal excision was done and immunohistochemistry revealed the tumor to be a growth hormone-secreting tumor.
垂体是在妊娠第六至八周期间复杂、精细且精确的神经胚胎学事件的结果下发育而成。一些异位细胞残余可发展为腺瘤。罕见的是,斜坡处的这些细胞残余可能是腺瘤形成的部位。我们的患者是一名35岁经产妇,因肢端肥大症接受治疗,影像学检查发现斜坡有占位性病变。进行了经蝶窦切除术,免疫组化显示该肿瘤为分泌生长激素的肿瘤。