Shenker Y, LLoyd R V, Weatherbee L, Port F K, Grekin R J, Barkan A L
J Clin Endocrinol Metab. 1986 May;62(5):1065-9. doi: 10.1210/jcem-62-5-1065.
In a patient with hyperparathyroidism and chronic renal failure due to polycystic kidney disease, a finding of destroyed sellar and parasellar structures and hyperprolactinemia suggested the diagnosis of invasive pituitary prolactinoma. At surgery no tumor was found, and pathological examination of the sphenoid bone revealed a parathyroid bone lesion (brown tumor) as well as ectopic prolactinoma in the clivus. This patient demonstrates that a tumor may develop in ectopic pituitary tissue. The combination of radiographically abnormal sellar structures with pituitary hormone hypersecretion should not be regarded as absolute proof of a pituitary adenoma.
在一名因多囊肾病导致甲状旁腺功能亢进和慢性肾衰竭的患者中，蝶鞍和鞍旁结构破坏以及高泌乳素血症的表现提示侵袭性垂体泌乳素瘤的诊断。手术时未发现肿瘤，蝶骨的病理检查显示甲状旁腺骨病变（棕色瘤）以及斜坡处的异位泌乳素瘤。该患者表明肿瘤可在异位垂体组织中发生。蝶鞍结构影像学异常与垂体激素分泌过多的组合不应被视为垂体腺瘤的确凿证据。
