Mohapatra S, Pradhan B B, Satpathy U K, Mohanty Arati, Pattnaik J R
Department of Physiology, S.C.B. Medical College, Cuttack.
Indian J Physiol Pharmacol. 2007 Apr-Jun;51(2):160-4.
Thrombocytopenia is an associated phenomenon of Pregnancy induced hypertension (PIH). But the accurate count of platelets either by manual, (direct or indirect methods) or by automated cell counters is not feasible for all patients at all hospitals. Therefore we have adopted the method of platelet estimation, not platelet count as an alternate procedure to estimate the degree of thrombocytopenia in patients with PIH cases. We included 30 normal pregnant women and 90 pregnant women with varying degree of PIH. Blood platelets were estimated by an accepted manual method. Platelet numbers were found to be 2.38 lacs/mm3 +/- 0.33 in control group, 2.23 lacs/mm3 +/- 0.19 in mild PIH, 1.82 lakhs/mm3 +/- 0.45 in pre eclampsia and 1.21 lacs/mm3 +/- 0.49 in eclampsia. This indicated that there is an inverse relationship between the severity of PIH and platelet numbers. So this method of platelet estimation is useful as a rapid method of assessment in PIH. This method is not only rapid and cheap but can be done even in rural hospital settings.
血小板减少是妊娠期高血压疾病（PIH）的一种相关现象。但对于所有医院的所有患者而言，通过手工（直接或间接方法）或自动血细胞计数器准确计数血小板并不可行。因此，我们采用了血小板估算方法，而非血小板计数，作为评估PIH患者血小板减少程度的替代程序。我们纳入了30名正常孕妇和90名不同程度PIH的孕妇。通过一种公认的手工方法估算血小板。对照组血小板计数为2.38万/mm³±0.33，轻度PIH组为2.23万/mm³±0.19，先兆子痫组为1.82万/mm³±0.45，子痫组为1.21万/mm³±0.49。这表明PIH的严重程度与血小板数量呈负相关。所以这种血小板估算方法作为PIH的一种快速评估方法很有用。这种方法不仅快速且成本低廉，甚至在农村医院环境中也能进行。
