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一名终末期肾病患者的孤立性小脑可逆性白质脑病综合征

Isolated cerebellar reversible leukoencephalopathy syndrome in a patient with end stage renal disease.

作者信息

Lim Min Hee, Kim Dong Wook, Cho Hyun Seop, Lee Hyeon Jeong, Kim Hyun-Jung, Park Ki-Jong, Chang Se-Ho, Park Dong Jun

机构信息

Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, South Korea.

出版信息

Intern Med. 2008;47(1):43-5. doi: 10.2169/internalmedicine.47.0461. Epub 2008 Jan 1.

Abstract

We report an adult end-stage renal disease patient with only cerebellum involvement of reversible posterior leukoencephalopathy syndrome (RPLS). A 37-year-old woman, diagnosed as chronic glomerulonephritis, was admitted to our hospital with progressive visual disturbance and severe headache. MRI revealed hyperintense signal intensity changes restricted in the cortex and subcortical white matter of the cerebellum. With appropriate control of blood pressure and intracranial pressure, her symptoms were improved and complete resolution of previous hyperinternse lesion was shown on MRI after the 19th day of admission. This is first case of isolated cerebellar involvement of RPLS without other cerebral involvement in an adult.

摘要

我们报告了一名仅小脑受累的成人终末期肾病患者,其患有可逆性后部白质脑病综合征(RPLS)。一名37岁女性,被诊断为慢性肾小球肾炎,因进行性视力障碍和严重头痛入院。MRI显示高信号强度变化局限于小脑的皮质和皮质下白质。通过适当控制血压和颅内压,她的症状得到改善,入院第19天后MRI显示先前的高信号病变完全消退。这是首例成人RPLS仅孤立性小脑受累而无其他脑部受累的病例。

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