Christofidis Ch, Anastasiou A, Krasnikova E, Mandros Ch, Potolidis E
Second Internal Medicine Department, Volos General Hospital, Volos, Greece.
Neurology Department, Volos General Hospital, Volos, Greece.
Hippokratia. 2019 Jul-Sep;23(3):131-134.
Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome, which is presented with headache, seizures, altered mental consciousness, and visual disturbances, and is characterized by white matter vasogenic edema, predominantly affecting the posterior occipital and parietal lobes of the brain. This clinical syndrome is increasingly recognized due to the improvement and availability of brain imaging and, more specifically, magnetic resonance imaging.
We report the case of an otherwise healthy 20-year-old female who presented with fever, headache, and generalized arthralgia, raising the suspicion of serotype B meningitis, which was later complicated by PRES. The patient was treated with the antiepileptic drug levetiracetam, mannitol, and dexamethasone. Her mental status was completely restored in 3-4 days after the initiation of the treatment for PRES and was characterized by rapid clinical recovery.
PRES is a neurotoxic state characterized by a unique brain imaging pattern typically associated with a number of complex clinical conditions including infection, sepsis, and shock. The syndrome should be promptly recognized since it is reversible and treatable. HIPPOKRATIA 2019, 23(2): 131-134.
后部可逆性脑病综合征（PRES）是一种临床-放射学综合征，表现为头痛、癫痫发作、意识改变和视觉障碍，其特征为白质血管源性水肿，主要累及大脑枕叶和顶叶后部。由于脑成像技术尤其是磁共振成像技术的改进和普及，这种临床综合征越来越受到认可。
我们报告一例20岁健康女性病例，该患者出现发热、头痛和全身关节痛，起初怀疑为B型血清型脑膜炎，后来并发PRES。患者接受了抗癫痫药物左乙拉西坦、甘露醇和地塞米松治疗。在开始治疗PRES后的3 - 4天，她的精神状态完全恢复，其特点是临床恢复迅速。
PRES是一种神经毒性状态，其特征是具有独特的脑成像模式，通常与多种复杂的临床病症相关，包括感染、脓毒症和休克。该综合征应尽早识别，因为它是可逆的且可治疗。《希波克拉底》2019年，第23卷第2期：131 - 134页。
