Bacci Gaetano, Palmerini Emanuela, Staals Eric L, Ferrari Stefano, Battaglia Milva, Longhi Alessandra, Bertoni Franco, Briccoli Antonio
Division of Chemotherapy, Istituto Ortopedico Rizzoli, Bologna, Italy.
J Pediatr Hematol Oncol. 2008 Jan;30(1):90-2. doi: 10.1097/MPH.0b013e31815cc410.
A case of spontaneous regression of a pulmonary metastasis from high-grade osteosarcoma is reported. The metastasis developed 5 years after chemotherapy and amputation for a distal femur osteosarcoma. The sarcomatous nature of the lesion was histologically confirmed. No treatment was attempted owing to the patient's refusal. The patient was followed up every 3 months and a spontaneous regression of the lesion was documented. Seven years after the diagnosis of lung metastases, no pulmonary nodules or other signs of relapse are present.
报告了一例高级别骨肉瘤肺转移灶自发消退的病例。该转移灶在化疗及股骨远端骨肉瘤截肢术后5年出现。病变的肉瘤性质经组织学证实。由于患者拒绝,未尝试进行治疗。每3个月对患者进行随访,记录到病变出现自发消退。在诊断肺转移7年后,未发现肺结节或其他复发迹象。