[全身性水肿，两名胰腺癌患者接受吉西他滨化疗后的并发症]

[Anasarca, a complication of chemotherapy with gemcitabine in two patients with pancreatic cancer].

作者信息

Dahan Laetitia, Ressiot Emmanuelle, Cournede Agnès, Ries Pauline, Duluc Muriel, Laquiere Arthur, Laugier René, Braguer Diane, Seitz Jean-François

机构信息

Service d'hépatogastroentérologie et oncologie digestive; Marseille.

出版信息

Gastroenterol Clin Biol. 2007 Dec;31(12):1143-5. doi: 10.1016/s0399-8320(07)78353-7.

DOI:10.1016/s0399-8320(07)78353-7

PMID:18176375

Abstract

Pancreatic adenocarcinoma is the fifth most common cause of cancer-related mortality in the world. The nucleoside analogue gemcitabine is the established standard therapy for advanced disease. Rare cases of gemcitabine-associated systemic capillary leak syndrome have been reported. Here, we present two cases of capillary-leak syndrome in patients with pancreatic cancer treated with gemcitabine.

摘要

胰腺腺癌是全球癌症相关死亡的第五大常见原因。核苷类似物吉西他滨是晚期疾病的既定标准疗法。已有吉西他滨相关的系统性毛细血管渗漏综合征的罕见病例报道。在此，我们报告两例接受吉西他滨治疗的胰腺癌患者发生毛细血管渗漏综合征的病例。