Azevedo Luciana Reis, Dos Santos Jean Nunes, De Lima Antônio Adilson Soares, Machado Maria Angela Naval, Grégio Ana Maria Trindade
Department of Oral Medicine at School of Dentistry at Pontifícia Universidade Católica do Paraná in Curitiba, Paraná, Brazil.
J Contemp Dent Pract. 2008 Jan 1;9(1):91-7.
The purpose of this report is to present the clinical and histological features of a canalicular adenoma (CA) occurring in the upper lip and vestibular fornix of a 62-year-old woman.
CA is an uncommon benign salivary gland tumor occurring almost exclusively in the intraoral glands. This tumor has often been referred to as a variant of the basal cell adenoma. However, the World Health Organization's latest histological classification of salivary gland tumors recognizes it as a separate entity under the broader heading of monomorphic adenoma, which is not related to any of the subtypes of basal cell adenomas.
A 62-year-old woman with a chief complaint of an extraoral swelling in the upper lip. The evolution of the lesion was not known by the patient who recognized it when she touched her upper lip and found "an acne" on it. The patient wore complete dentures since age 17 and was not aware of any pain or tenderness in the area. Extra and intraoral examination revealed a mobile nodular lesion located in the right aspect of the upper lip near the nose and in the vestibular fornix between the lateral incisor and canine. Microscopic examination confirmed the final diagnosis of CA. The patient is currently free of disease 54 months after surgical excision of the tumor.
Local excision of symptomatic nodules seems to be sufficient to manage patients with multifocal CA.10 But, unlike other benign tumors, CA may need a longer follow-up due to its tendency towards multifocal occurrence and late recurrence.
本报告旨在呈现一名62岁女性上唇及前庭沟发生的管状腺瘤(CA)的临床和组织学特征。
CA是一种罕见的良性涎腺肿瘤,几乎仅发生于口腔内腺体。该肿瘤常被认为是基底细胞腺瘤的一种变异型。然而,世界卫生组织最新的涎腺肿瘤组织学分类将其在单形性腺瘤这一广义范畴下视为一个独立实体,与基底细胞腺瘤的任何亚型均无关联。
一名62岁女性,主诉上唇有口外肿胀。患者自17岁起佩戴全口义齿,触碰到上唇发现“一颗粉刺”时才意识到该病变,此前并不知晓其演变情况。患者未察觉到该区域有任何疼痛或压痛。口外及口内检查发现一个可活动的结节状病变,位于上唇右侧靠近鼻部处以及侧切牙与尖牙之间的前庭沟。显微镜检查确诊为CA。该患者在肿瘤手术切除54个月后目前无疾病复发。
对于有症状的结节,局部切除似乎足以治疗多灶性CA患者。但与其他良性肿瘤不同,由于CA有多发倾向及晚期复发的特点,可能需要更长时间的随访。