• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

穿透性胎盘植入:甲氨蝶呤治疗及磁共振成像表现

Placenta percreta: methotrexate treatment and MRI findings.

作者信息

Heiskanen Nonna, Kröger Jaana, Kainulainen Sakari, Heinonen Seppo

机构信息

Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland.

出版信息

Am J Perinatol. 2008 Feb;25(2):91-2. doi: 10.1055/s-2007-1004831. Epub 2008 Jan 4.

DOI:10.1055/s-2007-1004831
PMID:18176907
Abstract

Our patient was a 24-year-old gravida 2 para 0 woman. After delivery, placenta percreta was noticed. There was no postpartum hemorrhage, and the patient desired future pregnancies. Although placenta percreta is rare, its sequelae include potentially lethal hemorrhage and loss of reproduction function. Placenta percreta was confirmed histologically and with ultrasonography and magnetic resonance imaging (MRI). Placenta percreta was treated conservatively with methotrexate. On follow-up, MRI showed a small calcified transmural extension of the placenta throughout the uterus in the right fundal area. Color Doppler ultrasonography showed no blood flow in the corresponding area, and maternal serum human chorionic gonadotropin (hCG) was undetectable. Use of MRI is a new method to detect abnormal placentation, and it could be used on follow-up in selective cases with other follow-up modalities. However, it seems likely that conservative management to preserve future fertility remains a secured and reasonable alternative when a patient has no active bleeding.

摘要

我们的患者是一名24岁、孕2产0的女性。分娩后,发现存在穿透性胎盘植入。患者没有产后出血,并且希望未来再次怀孕。虽然穿透性胎盘植入很少见,但其后遗症包括潜在的致命性出血和生殖功能丧失。通过组织学检查、超声检查和磁共振成像(MRI)确诊为穿透性胎盘植入。采用甲氨蝶呤对穿透性胎盘植入进行保守治疗。随访时,MRI显示胎盘在子宫右底部区域有一小片钙化的全层延伸。彩色多普勒超声显示相应区域无血流,且母体血清人绒毛膜促性腺激素(hCG)检测不到。MRI的应用是检测胎盘植入异常的一种新方法,在选择性病例中可与其他随访方式一起用于随访。然而,当患者没有活动性出血时,保留未来生育能力的保守治疗似乎仍是一种安全且合理的选择。

相似文献

1
Placenta percreta: methotrexate treatment and MRI findings.穿透性胎盘植入:甲氨蝶呤治疗及磁共振成像表现
Am J Perinatol. 2008 Feb;25(2):91-2. doi: 10.1055/s-2007-1004831. Epub 2008 Jan 4.
2
Magnetic resonance imagining (MRI) and serial beta-human chorionic gonadotrophin (beta-hCG) follow up for placenta percreta.磁共振成像(MRI)及连续检测β-人绒毛膜促性腺激素(β-hCG)以随访胎盘植入。
Arch Gynecol Obstet. 2007 Oct;276(4):371-3. doi: 10.1007/s00404-007-0351-3. Epub 2007 Mar 14.
3
Nonsurgical management of placenta percreta: a case report.
Obstet Gynecol. 1994 May;83(5 Pt 2):847-9.
4
Antenatal diagnosis of placenta percreta with planned in situ retention and methotrexate therapy in a woman infected with HIV.一名感染艾滋病毒的女性胎盘植入的产前诊断及计划原位保留和甲氨蝶呤治疗
Ultrasound Obstet Gynecol. 2002 Jul;20(1):90-3. doi: 10.1046/j.1469-0705.2002.00691.x.
5
Preservation of fertility and subsequent childbirth after methotrexate treatment of placenta percreta: a case report.甲氨蝶呤治疗穿透性胎盘植入后生育力的保留及后续分娩:一例报告
J Med Case Rep. 2015 Oct 19;9:232. doi: 10.1186/s13256-015-0716-3.
6
Placenta increta: Use of dynamic MRI for diagnosis and evaluation of placental vascularity.胎盘植入:动态磁共振成像在胎盘植入诊断及胎盘血管评估中的应用
Eur J Obstet Gynecol Reprod Biol. 2007 Sep;134(1):131-3. doi: 10.1016/j.ejogrb.2006.07.030. Epub 2006 Sep 7.
7
Placenta percreta: ultrasound diagnosis and conservative surgical management.穿透性胎盘植入:超声诊断与保守性手术治疗
Obstet Gynecol. 1988 Mar;71(3 Pt 2):454-6.
8
Difficulty of the surgical management of a case with placenta percreta invading towards parametrium.胎盘植入侵犯至子宫旁组织病例的手术处理难点
J Obstet Gynaecol Res. 2008 Jun;34(3):402-4. doi: 10.1111/j.1447-0756.2008.00780.x.
9
Placenta percreta invading the urinary bladder.穿透性胎盘植入侵犯膀胱。
Arch Gynecol Obstet. 2005 Mar;271(3):274-5. doi: 10.1007/s00404-004-0651-9. Epub 2004 Jul 27.
10
MRI appearance of placenta percreta and placenta accreta.穿透性胎盘植入和胎盘植入的磁共振成像表现。
Magn Reson Imaging. 1999 Sep;17(7):965-71. doi: 10.1016/s0730-725x(99)00035-1.

引用本文的文献

1
The use of methotrexate in the management of placenta accreta spectrum: a narrative review.甲氨蝶呤在胎盘植入谱系疾病管理中的应用:一项叙述性综述。
Ann Med Surg (Lond). 2025 Jul 11;87(9):5637-5643. doi: 10.1097/MS9.0000000000003524. eCollection 2025 Sep.
2
A Case of Placenta Percreta Managed with Sequential Embolisation Procedures.一例采用序贯栓塞术治疗的穿透性胎盘植入病例。
Case Rep Obstet Gynecol. 2018 Mar 15;2018:7213689. doi: 10.1155/2018/7213689. eCollection 2018.
3
Placenta percreta resulting in incomplete spontaneous abortion in first trimester.
穿透性胎盘植入导致孕早期不全自然流产。
Int J Fertil Steril. 2014 Oct;8(3):347-50. Epub 2014 Nov 1.
4
Invasive placentation and uterus preserving treatment modalities: a systematic review.侵袭性胎盘和保留子宫的治疗方法:系统评价。
Arch Gynecol Obstet. 2011 Aug;284(2):491-502. doi: 10.1007/s00404-011-1934-6. Epub 2011 Jun 3.
5
Preservation of fertility following abnormally adherent placenta treated conservatively: a case report.保守治疗异常粘连胎盘后生育能力的保留:一例报告
Cases J. 2009 Dec 18;2:9349. doi: 10.1186/1757-1626-2-9349.