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[酒精性谵妄、酒精性幻觉症及慢性酒精中毒患者在接受氯美噻唑、氟哌啶醇或利血平负荷试验时各群组的血浆促肾上腺皮质激素、生长激素及其他激素水平]

[Plasma ACTH, STH and other hormone levels in various groups under chlormethiazole, haloperidol or reserpine load in alchohol delirium, alcoholic hallucinations, and chronic alcoholism].

作者信息

Dobrzański T, Pieschl D

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1976 Jan;28(1):26-32.

PMID:181772
Abstract

Studies of 135 men with safely diagnosed alcohol delirium mostly revealed increased ACTH blood values when sober and increased T4 values in about 1/3 of these patients. There is a correlation between the psychiatric clinical picture of the alcohol delirium and the ACTH content of the plasma. Under load with chloromethiazole, halperidole or with reserpine, there is a significant drop in the increased ACTH and T4 values. In an acute alcoholic hallucinosis (n=16) similar endocrinological changes as in most cases of safely diagnosed alcohol delirium were observed. In a chronic alcoholic hallucinosis (n=11) and in chronic alcoholics (n=31) the endocrinological values were similar to those of patients after alcohol delirium.

摘要

对135名已确诊为酒精性谵妄的男性进行的研究大多显示,清醒时促肾上腺皮质激素(ACTH)血液值升高,约1/3的患者甲状腺素(T4)值升高。酒精性谵妄的精神科临床表现与血浆ACTH含量之间存在相关性。在使用氯美噻唑、氟哌啶醇或利血平负荷后,升高的ACTH和T4值会显著下降。在急性酒精性幻觉症(n = 16)中,观察到与大多数已确诊的酒精性谵妄病例类似的内分泌变化。在慢性酒精性幻觉症(n = 11)和慢性酗酒者(n = 31)中,内分泌值与酒精性谵妄后患者的内分泌值相似。

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