Suppr超能文献

鼻咽癌患者颞骨放射性骨坏死的外科治疗

Surgical treatment of osteoradionecrosis of the temporal bone in patients with nasopharyngeal carcinoma.

作者信息

Xu Y-D, Ou Y-K, Zheng Y-Q, Zhang S-Y

机构信息

Department of Otolaryngology, Second Affiliated Hospital of Sun Yat-Sen University, Guangzhou, PR China.

出版信息

J Laryngol Otol. 2008 Nov;122(11):1175-9. doi: 10.1017/S0022215107001399. Epub 2008 Jan 7.

Abstract

OBJECTIVE

To investigate methods of treating diffuse osteoradionecrosis of the temporal bone in cases of nasopharyngeal carcinoma, following radiotherapy.

STUDY DESIGN

Retrospective.

METHODS

Fourteen post-irradiation nasopharyngeal carcinoma patients (n = 14 ears) with diffuse osteoradionecrosis received surgical treatment from March 1994 to May 2005. The patients underwent radical mastoidectomy (five ears), extensive radical mastoidectomy (one ear), or radical mastoidectomy and obliteration with local vascularised fascia flaps (eight ears).

RESULTS

Six ears fully recovered; two ears were still infectious but sequestrum had not re-formed; five ears (50 per cent) still had repeated suppuration and did not epithelialise; and one ear had local re-formation of sequestrum requiring periodic dressing changes.

CONCLUSION

Diffuse osteoradionecrosis of the temporal bone following radiotherapy for nasopharyngeal carcinoma is difficult to treat surgically. The main objective of surgery is to facilitate drainage and to prevent complications. Radical mastoidectomy and obliteration with local vascularised flaps is an effective method.

摘要

目的

探讨鼻咽癌放疗后颞骨弥漫性放射性骨坏死的治疗方法。

研究设计

回顾性研究。

方法

1994年3月至2005年5月,14例放疗后鼻咽癌伴颞骨弥漫性放射性骨坏死患者(共14耳)接受了手术治疗。患者接受了根治性乳突切除术(5耳)、扩大根治性乳突切除术(1耳)或根治性乳突切除术并采用局部带血管筋膜瓣填塞术(8耳)。

结果

6耳完全恢复;2耳仍有感染,但死骨未再形成;5耳(50%)仍反复化脓且未上皮化;1耳局部死骨重新形成,需要定期换药。

结论

鼻咽癌放疗后颞骨弥漫性放射性骨坏死手术治疗困难。手术的主要目的是促进引流并预防并发症。根治性乳突切除术并采用局部带血管瓣填塞术是一种有效的方法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验